Leishmaniasis in humans: drug or vaccine therapy?

M Ghorbani, R Farhoudi - Drug design, development and therapy, 2017 - Taylor & Francis
Leishmania is an obligate intracellular pathogen that invades phagocytic host cells.
Approximately 30 different species of Phlebotomine sand flies can transmit this parasite …

Advances in leishmaniasis

HW Murray, JD Berman, CR Davies, NG Saravia - The Lancet, 2005 - thelancet.com
Governed by parasite and host factors and immunoinflammatory responses, the clinical
spectrum of leishmaniasis encompasses subclinical (inapparent), localised (skin lesions) …

Vaccines for visceral leishmaniasis: A review

K Jain, NK Jain - Journal of immunological methods, 2015 - Elsevier
Visceral leishmaniasis, which is also known as Kala-Azar, is one of the most severely
neglected tropical diseases recognized by the World Health Organization (WHO). The threat …

The prevention of canine leishmaniasis and its impact on public health

D Otranto, F Dantas-Torres - Trends in parasitology, 2013 - cell.com
Canine leishmaniasis (CanL) caused by Leishmania infantum is a vector-borne disease of
great veterinary and medical significance. Prevention of CanL requires a combined …

Canine leishmaniosis–new concepts and insights on an expanding zoonosis: part two

G Miro, L Cardoso, MG Pennisi, G Oliva, G Baneth - Trends in parasitology, 2008 - cell.com
Canine leishmaniosis is a widely spread zoonosis that is potentially fatal to humans and
dogs. Infection with Leishmania infantum is considerably more prevalent than clinical …

One Health: the global challenge of epidemic and endemic leishmaniasis

CB Palatnik-de-Sousa, MJ Day - Parasites & vectors, 2011 - Springer
Abstract'One Health'proposes the unification of medical and veterinary sciences with the
establishment of collaborative ventures in clinical care, surveillance and control of cross …

Current status on prevention and treatment of canine leishmaniasis

RM Reguera, M Moran, Y Perez-Pertejo… - Veterinary …, 2016 - Elsevier
Canine leishmaniasis (CanL) is a parasite-borne disease mainly induced by Leishmania
infantum in the Old World and Leishmania chagasi (infantum) in the New World. CanL is a …

Immunology of canine leishmaniasis

CL Barbiéri - Parasite immunology, 2006 - Wiley Online Library
The role of dogs as the main reservoir of visceral leishmaniasis has led to an increased
interest in the immune responses and in Leishmania antigens implicated in protective …

Epidemiological aspects of canine visceral leishmaniosis in the Islamic Republic of Iran

M Mohebali, H Hajjaran, Y Hamzavi, I Mobedi… - Veterinary …, 2005 - Elsevier
An epidemiological study to examine the sero-prevalence of zoonotic visceral leishmaniosis
(ZVL) among domestic and wild canines in endemic foci of Iran was carried out during 1999 …

Vaccines for leishmaniasis in the fore coming 25 years

CB Palatnik-de-Sousa - Vaccine, 2008 - Elsevier
Human vaccination against leishmaniasis using live Leishmania was used in Middle East
and Russia (1941–1980). First-generation vaccines, composed by killed parasites induce …