Osteoarthritis results in irreparable loss of articular cartilage. Due to its avascular nature and
low mitotic activity, cartilage has little intrinsic capacity for repair. Cartilage loss leads to pain …

Articular cartilage has a complex structure and metabolism which allow for a proper
movement within joints. Nevertheless, several systemically administered pharmacological …

Pathological angiogenesis is a crucial attribute of several chronic diseases such as cancer,
age-related macular degeneration, and osteoarthritis (OA). In the case of OA, pathological …

Background/objective Osteoarthritis (OA) is the most common joint disorder. Angiogenesis
and synovial hyperplasia are important factors in the development of OA. Previous studies …

Articular cartilage has a limited regenerative capacity, resulting in poor spontaneous healing
of damaged tissue. Despite various scientific efforts to enhance cartilage repair, no single …

Osteoarthritis (OA) commonly results in compromised mobility and disability, thereby
imposing a significant burden on healthcare systems. Cartilage injury is a prevalent …

The development of efficacious antitumor compounds with minimal toxicity is a hot research
topic. Numerous cancer cell targeted agents are evaluated daily in laboratories for their …

Therapeutic antibodies are attractive treatment options for numerous diseases based on
their ability to target and bind to specific proteins or antigens. Bevacizumab, an …

Osteoarthritis (OA) is the most common joint disease, affecting hundreds of millions of
people globally, which leads to a high cost of treatment and further medical care and an …

Increased levels of unconjugated bilirubin are neurotoxic, but the mechanism leading to
neurological damage has not been completely elucidated. Innovative strategies of …