Harnessing photocatalytic and electrochemical approaches for C–H bond trifluoromethylation and fluoroalkylation
Owing to the importance of trifluoromethyl (CF3) and related moieties in pharmaceuticals
and agrochemicals, the photoinduced and electrochemical− enabled redox functionalisation …
and agrochemicals, the photoinduced and electrochemical− enabled redox functionalisation …
Drug repurposing for spinal cord injury: progress towards therapeutic intervention for primary factors and secondary complications
Spinal cord injury (SCI) encompasses a plethora of complex mechanisms like the
involvement of major cell death pathways, neurodegeneration of spinal cord neurons …
involvement of major cell death pathways, neurodegeneration of spinal cord neurons …
Multiple 3D-and 2D-quantitative structure–activity relationship models (QSAR), theoretical study and molecular modeling to identify structural requirements of …
Tuberculosis (TB), an infectious remains a global health burden till date. Considering
immense importance of theoretical tools in computer aided-drug designing, the current study …
immense importance of theoretical tools in computer aided-drug designing, the current study …
Simple and efficient PET and AIEE mechanism-based fluorescent probes for sensing Tabun mimic DCNP
The highly sensitive, selective, easy-to-prepare, aqueous media based on two novel probes
2-(pyren-1-yl) imidazo [1, 2-a] pyridine (IMP-Py) and (2-(pyren-1-yl) imidazo [1, 2-a] pyridin-3 …
2-(pyren-1-yl) imidazo [1, 2-a] pyridine (IMP-Py) and (2-(pyren-1-yl) imidazo [1, 2-a] pyridin-3 …
Identification of an imidazopyridine-based compound as an oral selective estrogen receptor degrader for breast cancer therapy
M Pan, V Solozobova, NC Kuznik, N Jung… - Cancer Research …, 2023 - AACR
The pro-oncogenic activities of estrogen receptor alpha (ERα) drive breast cancer
pathogenesis. Endocrine therapies that impair the production of estrogen or the action of the …
pathogenesis. Endocrine therapies that impair the production of estrogen or the action of the …
Multicomponent Cross-Dehydrogenative Coupling of Imidazo[1,2-a]pyridine: Access to Abnormal Mannich and Mannich-Type Reaction
S Rahaman, SS Sahay, A Kumari… - The Journal of Organic …, 2024 - ACS Publications
This study showcases successfully switchable approaches to accomplish the C3-aryl
methylation and C3-amino methylation of privileged nitrogen-containing pharmaceutical …
methylation and C3-amino methylation of privileged nitrogen-containing pharmaceutical …
Synthesis, characterization, crystal structure, Hirshfeld analysis and theoretical investigation of 5-(4-methoxyphenyl)-7-phenyl-2-(pyridin-2-yl) imidazo [1, 2-a] pyridine …
Abstract Synthesis of 5-(4-methoxyphenyl)-7-phenyl-2-(pyridin-2-yl) imidazo [1, 2-a] pyridine-
8-carbonitrile has been carried out by the reaction between 1-(pyridin-2-yl) ethanone and 2 …
8-carbonitrile has been carried out by the reaction between 1-(pyridin-2-yl) ethanone and 2 …
Cu-catalysed diversity-oriented synthesis of isoxazole and imidazo [1, 2-a] azine conjugates
D Singh, S Sharma, RK Thakur, S Nain, CC Malakar… - Tetrahedron, 2024 - Elsevier
The first synthesis of diversely substituted isoxazole linked imidazo [1, 2-a] azine derivatives
via application of the Groebke-Blackburn-Bienayme (GBB) reaction with excellent yields is …
via application of the Groebke-Blackburn-Bienayme (GBB) reaction with excellent yields is …
Reaction of imidazo [1, 2-a] pyridines with coumarin-3-carboxylic acids: a domino Michael addition/decarboxylation/oxidation/annulation
A facile, metal-and additive-free C–C bond construction between imidazo [1, 2-a] pyridines
and coumarin-3-carboxylic acids through a decarboxylative Michael addition is reported to …
and coumarin-3-carboxylic acids through a decarboxylative Michael addition is reported to …
Synthesis of Membrane-Permeable Macrocyclic Peptides via Imidazopyridinium Grafting
Macrocyclic peptides (MPs) are a class of compounds that have been shown to be
particularly well suited for engaging difficult protein targets. However, their utility is limited by …
particularly well suited for engaging difficult protein targets. However, their utility is limited by …