Normal wound healing progresses through inflammatory, proliferative and remodeling
phases in response to tissue injury. Collagen, a key component of the extracellular matrix …

Collagen occurs in nature with a dedicated triple helix structure and is the most preferred
biomaterial in commercialized medical products. However, concerns on purity, disease …

Functional repair of osteochondral (OC) tissue remains challenging because the transition
from bone to cartilage presents gradients in biochemical and physical properties necessary …

Genetically encoded collagen-like protein-based hydrogels have demonstrated remarkable
efficacy in promoting the healing process in diabetic patients. However, the current methods …

Incorporating zinc oxide nanoparticles (ZnOnps) into collagen is a promising strategy for
fabricating biomaterials with excellent antibacterial activity, but modifications are necessary …

The role of interferon-alpha is critical in modulating immune responses and the wound
healing process. However, the rapid degradation and short lifespan of IFN-α in the body limit …

Recapitulation of the articular cartilage microenvironment for regenerative medicine
applications faces significant challenges due to the complex and dynamic biochemical and …

Natural animal collagen and its recombinant collagen are favourable replacements in
human tissue engineering due to their remarkable biomedical property. However, this …

The extracellular matrix is a highly complex microenvironment, whose various components
converge to regulate cell fate. Hydrogels, as water-swollen polymer networks composed by …

We present a collagen-mimetic protein of bacterial origin based upon a modified subdomain
of the collagen-like Sc12 protein from Streptococcus pyogenes, as an alternative collagen …