Type II bacterial toxin–antitoxins: hypotheses, facts, and the newfound plethora of the PezAT system

WT Chan, MP Garcillán-Barcia, CC Yeo… - FEMS Microbiology …, 2023 - academic.oup.com
Toxin–antitoxin (TA) systems are entities found in the prokaryotic genomes, with eight
reported types. Type II, the best characterized, is comprised of two genes organized as an …

A 3'UTR-derived small RNA represses pneumolysin synthesis and facilitates pneumococcal brain invasion

K Shen, W Miao, L Zhu, Q Hu, F Ren, X Dong… - Communications …, 2024 - nature.com
Abstract Pneumolysin (Ply) of Streptococcus pneumoniae (pneumococcus) at relatively high
and low levels facilitates pneumococcal invasion into the lung and brain, respectively; …

[HTML][HTML] Influenza A virus modulation of Streptococcus pneumoniae infection using ex vivo transcriptomics in a human primary lung epithelial cell model reveals …

A D'Mello, JR Lane, JL Tipper, E Martínez… - Biorxiv, 2023 - ncbi.nlm.nih.gov
Background: Streptococcus pneumoniae (Spn) is typically an asymptomatic colonizer of the
nasopharynx but it also causes pneumonia and disseminated disease affecting various host …