DNA methylation-based predictors of health: applications and statistical considerations
DNA methylation data have become a valuable source of information for biomarker
development, because, unlike static genetic risk estimates, DNA methylation varies …
development, because, unlike static genetic risk estimates, DNA methylation varies …
Epigenome-wide association studies: current knowledge, strategies and recommendations
The aetiology and pathophysiology of complex diseases are driven by the interaction
between genetic and environmental factors. The variability in risk and outcomes in these …
between genetic and environmental factors. The variability in risk and outcomes in these …
Epigenetics of early cardiometabolic disease: mechanisms and precision medicine
AA Baccarelli, J Ordovás - Circulation Research, 2023 - Am Heart Assoc
Epigenetics has transformed our understanding of the molecular basis of complex diseases,
including cardiovascular and metabolic disorders. This review offers a comprehensive …
including cardiovascular and metabolic disorders. This review offers a comprehensive …
[HTML][HTML] Effects of ketogenic diet and ketone bodies on the cardiovascular system: Concentration matters
S Nasser, V Vialichka, M Biesiekierska… - World Journal of …, 2020 - ncbi.nlm.nih.gov
Ketone bodies have emerged as central mediators of metabolic health, and multiple
beneficial effects of a ketogenic diet, impacting metabolism, neuronal pathologies and, to a …
beneficial effects of a ketogenic diet, impacting metabolism, neuronal pathologies and, to a …
Association of cardiovascular health through young adulthood with genome-wide DNA methylation patterns in midlife: the CARDIA study
Background: Cardiovascular health (CVH) from young adulthood is strongly associated with
an individual's future risk of cardiovascular disease (CVD) and total mortality. Defining …
an individual's future risk of cardiovascular disease (CVD) and total mortality. Defining …
Clinical epigenetics settings for cancer and cardiovascular diseases: real-life applications of network medicine at the bedside
Despite impressive efforts invested in epigenetic research in the last 50 years, clinical
applications are still lacking. Only a few university hospital centers currently use epigenetic …
applications are still lacking. Only a few university hospital centers currently use epigenetic …
Recent updates and advances in the use of glycated albumin for the diagnosis and monitoring of diabetes and renal, cerebro-and cardio-metabolic diseases
Diabetes mellitus is a heterogeneous and dysmetabolic chronic disease in which the
laboratory plays a fundamental role, from diagnosis to monitoring therapy and studying …
laboratory plays a fundamental role, from diagnosis to monitoring therapy and studying …
[HTML][HTML] Residential surrounding greenness and DNA methylation: an epigenome-wide association study
Background DNA methylation is a potential biological mechanism through which residential
greenness affects health, but little is known about its association with greenness and …
greenness affects health, but little is known about its association with greenness and …
The influence of epigenetics and inflammation on cardiometabolic risks
S Raghubeer - Seminars in Cell & Developmental Biology, 2024 - Elsevier
Cardiometabolic diseases include metabolic syndrome, obesity, type 2 diabetes mellitus,
and hypertension. Epigenetic modifications participate in cardiometabolic diseases through …
and hypertension. Epigenetic modifications participate in cardiometabolic diseases through …
Association of cardiovascular health and epigenetic age acceleration
Background Cardiovascular health (CVH) has been defined by the American Heart
Association (AHA) as the presence of the “Life's Simple 7” ideal lifestyle and clinical factors …
Association (AHA) as the presence of the “Life's Simple 7” ideal lifestyle and clinical factors …