Diabetic vascular diseases: molecular mechanisms and therapeutic strategies

Y Li, Y Liu, S Liu, M Gao, W Wang, K Chen… - Signal transduction and …, 2023 - nature.com
Vascular complications of diabetes pose a severe threat to human health. Prevention and
treatment protocols based on a single vascular complication are no longer suitable for the …

AI-integrated ocular imaging for predicting cardiovascular disease: advancements and future outlook

Y Huang, CY Cheung, D Li, YC Tham, B Sheng… - Eye, 2024 - nature.com
Cardiovascular disease (CVD) remains the leading cause of death worldwide. Assessing of
CVD risk plays an essential role in identifying individuals at higher risk and enables the …

Association between retinal features from multimodal imaging and schizophrenia

SK Wagner, M Cortina-Borja, SM Silverstein… - JAMA …, 2023 - jamanetwork.com
Importance The potential association of schizophrenia with distinct retinal changes is of
clinical interest but has been challenging to investigate because of a lack of sufficiently large …

Integrating oculomics with genomics reveals imaging biomarkers for preventive and personalized prediction of arterial aneurysms

Y Huang, C Li, D Shi, H Wang, X Shang, W Wang… - EPMA Journal, 2023 - Springer
Objective Arterial aneurysms are life-threatening but usually asymptomatic before requiring
hospitalization. Oculomics of retinal vascular features (RVFs) extracted from retinal fundus …

[HTML][HTML] Transformative applications of oculomics-based AI approaches in the management of systemic diseases: A systematic review

Z Li, S Yin, S Wang, Y Wang, W Qiang… - Journal of Advanced …, 2024 - Elsevier
Background Systemic diseases, such as cardiovascular and cerebrovascular conditions,
pose significant global health challenges due to their high mortality rates. Early identification …

Artificial Intelligence and Diabetes Mellitus: An Inside Look Through the Retina

YS Bazargani, M Mirzaei, N Sobhi, M Abdollahi… - arXiv preprint arXiv …, 2024 - arxiv.org
Diabetes mellitus (DM) predisposes patients to vascular complications. Retinal images and
vasculature reflect the body's micro-and macrovascular health. They can be used to …

Diabetes and artificial intelligence beyond the closed loop: a review of the landscape, promise and challenges

SC Mackenzie, CAR Sainsbury, DJ Wake - Diabetologia, 2024 - Springer
The discourse amongst diabetes specialists and academics regarding technology and
artificial intelligence (AI) typically centres around the 10% of people with diabetes who have …

Using data to improve the management of diabetes: The Tayside experience

MK Siddiqui, C Hall, SG Cunningham… - Diabetes …, 2022 - Am Diabetes Assoc
Tayside is a region in the East of Scotland and forms one of nine local government regions
in the country. It is home to approximately 416,000 individuals who fall under the National …

Fine-mapping of retinal vascular complexity loci identifies Notch regulation as a shared mechanism with myocardial infarction outcomes

A Villaplana-Velasco, M Pigeyre, J Engelmann… - Communications …, 2023 - nature.com
There is increasing evidence that the complexity of the retinal vasculature measured as
fractal dimension, Df, might offer earlier insights into the progression of coronary artery …

Incremental Prognostic Value of a Coronary Heart Disease Polygenic Risk Score in Type 2 Diabetes

IR Mordi, I Li, G George, RJ McCrimmon… - Diabetes …, 2024 - diabetesjournals.org
OBJECTIVE The recent availability of cardiovascular risk-reducing type 2 diabetes (T2D)
therapies makes it imperative to optimally identify individuals who could derive benefit …