Aberrant methylation patterns in cancer: a clinical view

A Videtic Paska, P Hudler - Biochemia medica, 2015 - hrcak.srce.hr
Sažetak Epigenetic mechanisms, such as DNA methylation, DNA hydroxymethylation, post-
translational modifications (PTMs) of histone proteins affecting nucleosome remodelling …

Whole mitochondrial genome sequencing highlights mitochondrial impact in gastric cancer

GC Cavalcante, ANR Marinho, AK Anaissi… - Scientific reports, 2019 - nature.com
Mitochondria are organelles that perform major roles in cellular operation. Thus, alterations
in mitochondrial genome (mtGenome) may lead to mitochondrial dysfunction and cellular …

[HTML][HTML] A common molecular signature of intestinal-type gastric carcinoma indicates processes related to gastric carcinogenesis

R Binato, EC Santos, M Boroni, S Demachki… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Gastric carcinoma (GC) is one of the most aggressive cancers and the second leading
cause of cancer death in the world. According to the Lauren classification, this …

Combination of miRNA and RNA functions as potential biomarkers for gastric cancer

S Chen, J Zhu, F Yu, Y Tian, S Ma, X Liu - Tumor Biology, 2015 - Springer
Gastric cancer (GC) is the second leading cause of cancer-related death in the world. The
optimal treatment regimens for GC depend on tumor stage, histopathological subtype, and …

Long noncoding RNA aberrant expression profiles after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy of AGC ascertained by microarray …

X Zeng, H Shi, J Wang, S Cui, H Tang, X Zhang - Tumor Biology, 2015 - Springer
Long noncoding RNAs (lncRNAs) have been shown to be involved in the development and
progression of advanced gastric cancer (AGC). However, the roles of lncRNAs in advanced …

Reciprocal expression of p-AMPKa and p-S6 is strongly associated with the prognosis of gastric cancer

Z Zheng, Y Zheng, M Zhang, J Wang, G Yu, W Fang - Tumor Biology, 2016 - Springer
Activation of AMP-activated protein kinase (AMPK) suppressed mammalian target of
rapamycin (mTOR) pathway, resulting in impaired cancer cell proliferation. Two cohorts (50 …

Gastric Cancer Biomarker Candidates Identified by Machine Learning and Integrative Bioinformatics: Toward Personalized Medicine

VSP Sinnarasan, D Paul, R Das… - OMICS: A Journal of …, 2023 - liebertpub.com
Gastric cancer (GC) is among the leading causes of cancer-related deaths worldwide. The
discovery of robust diagnostic biomarkers for GC remains a challenge. This study sought to …

pRb2/p130 localizes to the cytoplasm in diffuse gastric cancer

L Cito, P Indovina, IM Forte, F Pentimalli… - Journal of Cellular …, 2015 - Wiley Online Library
Abstract pRb2/p130 is a key tumor suppressor, whose oncosuppressive activity has mainly
been attributed to its ability to negatively regulate cell cycle by interacting with the E2F4 and …

Effects of gene silencing of CypB on gastric cancer cells

F Guo, Y Zhang, CN Zhao, L Li, YJ Guo - Asian Pacific journal of tropical …, 2015 - Elsevier
Objective To determine the effect of gene silencing of cyclophilin B (CypB) on growth and
proliferation of gastric cancer cells. Methods CypB siRNA lentivirus (LV-CypB-si) and control …

Prognostic value of carcinoembryonic antigen levels in transoperative peritoneal lavage in patients with gastric cancer

LB Alves, MT Tsukazan, AE Serafim… - … Brasileiros de Cirurgia …, 2018 - SciELO Brasil
Background: The carcinoembryonic antigen level in peritoneal lavage has been showing to
be a reliable prognostic factor in gastric cancer. Aim: To identify any association between …