Dihydrotestosterone is a potent androgen metabolite formed from testosterone by action of
5α-reductase isoenzymes. Mutations in the type 2 isoenzyme cause a disorder of 46, XY sex …

abstract Context: In 46, XY disorders of sex development, 5α-reductase deficiency is rare
and is not usually the first-intention diagnosis in newborn ambiguous genitalia, contrary to …

Disorders of sex development (DSD) are defined as 'congenital conditions in which the
development of chromosomal, gonadal, or anatomical sex is atypical'[Lee et al., Pediatrics …

Individuals living with an intersex condition have not received much attention in counseling
psychology, although a high need for psychosocial care is obvious. Using a mixed-methods …

Individuals with male karyotype (46, XY) affected by 5α-reductase type 2 deficiency, a rare
autosomal recessive inherited disorder, can have an almost female phenotype or partially …

Background Studies regarding genetic and clinical characteristics, gender preference, and
gonadal malignancy rates for steroid 5-alpha-reductase type 2 deficiency (5α-RD2) are …

The observation of ambiguous genitalia in the newborn signals a medical, surgical and
psychological emergency. The most crucial decision will be the choice of sex assignment …

The goal of this study was to perform 5‐α‐reductase type 2 gene (SRD5A2) analysis in a
male pseudohermaphrodite (MPH) patient with normal testosterone (T) production and …

OBJECTIVE: To report a case of successful paternity from a male homozygous for 5α-
reductase-2 deficiency. DESIGN: Case report. SETTING: Academic center, division of …

Störungen der somatosexuellen Differenzierung mit am bivalentem, intersexuellem
äußerem Genitale treten bei ca. 1: 3.000 bis 1: 5.000 Neugeborenen auf und konfrontieren …