Neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and
amyotrophic lateral sclerosis (ALS), are characterized by the death of neurons within specific …

In aging and neurodegenerative diseases, loss of distinct type of neurons characterizes
disease-specific pathological and clinical features, and mitochondria play a pivotal role in …

A large number of diverse mechanisms that lead to cytoprotection have been described to
date. Perhaps, not surprisingly, the role of mitochondria in these phenomena is notable. In …

The incidence of cardiovascular and metabolic diseases has increased over the last
decades and is an important cause of death worldwide. An upcoming ingredient on the …

Anthocyanins are reported to exhibit a wide variety of remedial qualities against many
human disorders, including antioxidative stress, anti-inflammatory activity, amelioration of …

Neurodegeneration is the progressive loss of neuronal structures and functions that lead to
copious disorders like Alzheimer's (AD), Parkinson's (PD), Huntington's (HD), amyotrophic …

Background Neuroinflammation plays a major role in the development of ischemic stroke,
and regulation of the proinflammatory TLR4 signaling pathway in microglia stands to be a …

In neurodegenerative disorders, including Alzheimer's and Parkinson's disease,
neuroprotection by diet and natural bioactive compounds has been proposed to prevent the …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by a
decline in cognitive function and neuronal damage. Although the precise pathobiology of AD …

Rotenone is a widely used organic pesticide; its serious side effect for off‐target species is
neurotoxicity. The primary mechanism of rotenone toxicity is inhibition of the mitochondrial …