Role of stromal paracrine signals in proliferative diseases of the aging human prostate

K Ishii, S Takahashi, Y Sugimura… - Journal of Clinical …, 2018 - mdpi.com
Androgens are essential for the development, differentiation, growth, and function of the
prostate through epithelial–stromal interactions. However, androgen concentrations in the …

Plasma hsa_circ_0027089 is a diagnostic biomarker for hepatitis B virus-related hepatocellular carcinoma

K Zhu, H Zhan, Y Peng, L Yang, Q Gao, H Jia… - …, 2020 - academic.oup.com
Circular RNAs (circRNAs) have recently been identified as a new member of endogenous
noncoding RNAs. CircRNAs exhibit high stability and can thus can be used as valuable …

miR-425-5p as an exosomal biomarker for metastatic prostate cancer

MP Rode, AH Silva, J Cisilotto, D Rosolen… - Cellular …, 2021 - Elsevier
Prostate cancer-related deaths are mostly caused by metastasis, which indicates the
importance of identifying clinical prognostic biomarkers. In this study, we evaluated the …

miR‑148a, miR‑152 and miR‑200b promote prostate cancer metastasis by targeting DNMT1 and PTEN expression

V Gurbuz, S Sozen, CY Bilen… - Oncology …, 2021 - spandidos-publications.com
MicroRNAs (miRs) modulate the expression of target genes in the signal pathway on
transcriptome level. The present study investigated the 'epigenetic‑based miRNA (epi …

The role of miRNAin prostate cancer diagnosis, prognosisand treatment response: a narrative review

JR Vazquez-Urrutia, MI Torres-Bustamante… - Future …, 2023 - Taylor & Francis
To date, prostate cancer remains the most common tumor diagnosed in males and the
second most commoncause of cancer-related mortality. While current screening protocols …

Functional roles and potential clinical application of miRNA‐345‐5p in prostate cancer

I Tinay, M Tan, B Gui, L Werner, AS Kibel, L Jia - The Prostate, 2018 - Wiley Online Library
Background MicroRNAs (miRNAs) are small non‐coding RNAs, which negatively regulate
gene expression and impact prostate cancer (PCa) growth and progression. Circulating …

MiR-93/miR-375: diagnostic potential, aggressiveness correlation and common target genes in prostate cancer

E Ciszkowicz, P Porzycki, M Semik… - International Journal of …, 2020 - mdpi.com
Dysregulation of miRNAs has a fundamental role in the initiation, development and
progression of prostate cancer (PCa). The potential of miRNA in gene therapy and …

Characterization of proteins, mRNAs, and miRNAs of circulating extracellular vesicles from prostate cancer patients compared to healthy subjects

J Chisholm, S Haas-Neill, P Margetts… - Frontiers in …, 2022 - frontiersin.org
Prostate cancer (PC) is the fifth leading cause of death in men globally. Measurement of the
blood PSA level is still considered the gold-standard biomarker test for PC despite its high …

Differences between well-differentiated neuroendocrine tumors and ductal adenocarcinomas of the pancreas assessed by multi-omics profiling

T Starzyńska, J Karczmarski, A Paziewska… - International journal of …, 2020 - mdpi.com
Most pancreatic neuroendocrine tumors (PNETs) are indolent, while pancreatic ductal
adenocarcinomas (PDACs) are particularly aggressive. To elucidate the basis for this …

Vinculin orchestrates prostate cancer progression by regulating tumor cell invasion, migration, and proliferation

X Zheng, H Xu, L Gong, D Cao, T Jin, Y Wang… - The …, 2021 - Wiley Online Library
Abstract Background Prostate cancer (PCa) is a leading cause of death in men, and effective
treatment of PCa requires further development. Our study aimed to investigate the potential …