COVID-19, an emerging coronavirus infection: advances and prospects in designing and developing vaccines, immunotherapeutics, and therapeutics
The novel coronavirus infection (COVID-19 or Coronavirus disease 2019) that emerged from
Wuhan, Hubei province of China has spread to many countries worldwide. Efforts have been …
Wuhan, Hubei province of China has spread to many countries worldwide. Efforts have been …
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): a systemic infection
A Synowiec, A Szczepański… - Clinical microbiology …, 2021 - Am Soc Microbiol
To date, seven identified coronaviruses (CoVs) have been found to infect humans; of these,
three highly pathogenic variants have emerged in the 21st century. The newest member of …
three highly pathogenic variants have emerged in the 21st century. The newest member of …
SARS-CoV-2 infection depends on cellular heparan sulfate and ACE2
TM Clausen, DR Sandoval, CB Spliid, J Pihl… - Cell, 2020 - cell.com
We show that SARS-CoV-2 spike protein interacts with both cellular heparan sulfate and
angiotensin-converting enzyme 2 (ACE2) through its receptor-binding domain (RBD) …
angiotensin-converting enzyme 2 (ACE2) through its receptor-binding domain (RBD) …
SARS-CoV-2 infects cells after viral entry via clathrin-mediated endocytosis
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
COVID-19, so understanding its biology and infection mechanisms is critical to facing this …
COVID-19, so understanding its biology and infection mechanisms is critical to facing this …
[HTML][HTML] Human coronavirus-229E,-OC43,-NL63, and-HKU1 (Coronaviridae)
DX Liu, JQ Liang, TS Fung - Encyclopedia of virology, 2021 - ncbi.nlm.nih.gov
Seven human coronaviruses (HCoVs) have been so far identified, namely HCoV-229E,
HCoV-OC43, HCoV-NL63, HCoV-HKU1, severe acute respiratory syndrome coronavirus …
HCoV-OC43, HCoV-NL63, HCoV-HKU1, severe acute respiratory syndrome coronavirus …
The biology of lactoferrin, an iron-binding protein that can help defend against viruses and bacteria
DB Kell, EL Heyden, E Pretorius - Frontiers in immunology, 2020 - frontiersin.org
Lactoferrin is a nutrient classically found in mammalian milk. It binds iron and is transferred
via a variety of receptors into and between cells, serum, bile, and cerebrospinal fluid. It has …
via a variety of receptors into and between cells, serum, bile, and cerebrospinal fluid. It has …
Developing therapeutic approaches for twenty-first-century emerging infectious viral diseases
RM Meganck, RS Baric - Nature medicine, 2021 - nature.com
The twenty-first century has already recorded more than ten major epidemic or pandemic
virus emergence events, including the ongoing and devastating coronavirus disease 2019 …
virus emergence events, including the ongoing and devastating coronavirus disease 2019 …
Recent discovery and development of inhibitors targeting coronaviruses
T Pillaiyar, S Meenakshisundaram, M Manickam - Drug discovery today, 2020 - Elsevier
Human coronaviruses (CoVs) are enveloped viruses with a positive-sense single-stranded
RNA genome. Currently, six human CoVs have been reported including human coronavirus …
RNA genome. Currently, six human CoVs have been reported including human coronavirus …
Coronavirus disease 2019–COVID-19
In recent decades, several new diseases have emerged in different geographical areas, with
pathogens including Ebola virus, Zika virus, Nipah virus, and coronaviruses (CoVs) …
pathogens including Ebola virus, Zika virus, Nipah virus, and coronaviruses (CoVs) …
An overview on the seven pathogenic human coronaviruses
To date, seven human coronaviruses (HCoVs) have been detected: HCoV‐NL63, HCoV‐
229E, HCoV‐HKU1, HCoV‐OC43, severe acute respiratory syndrome coronavirus (SARS …
229E, HCoV‐HKU1, HCoV‐OC43, severe acute respiratory syndrome coronavirus (SARS …