Drugs to limit Zika virus infection and implication for maternal-fetal health

A Kumar, D Kumar, J Jose, R Giri, IU Mysorekar - Frontiers in virology, 2022 - frontiersin.org
Although the placenta has robust defense mechanisms that protect the fetus from a viral
infection, some viruses can manipulate or evade these mechanisms and disrupt physiology …

Modulation of cellular machineries by Zika virus‐encoded proteins

S Dong, MZX Xiao, Q Liang - Journal of Medical Virology, 2023 - Wiley Online Library
The strain of Zika virus (ZIKV) that circulated during the 2015 epidemic in Brazil has been
associated with more than 2000 cases of microcephaly from September 2015 through …

The Compound SBI-0090799 Inhibits Zika Virus Infection by Blocking De Novo Formation of the Membranous Replication Compartment

L Riva, S Goellner, SB Biering, CT Huang… - Journal of …, 2021 - Am Soc Microbiol
Zika virus (ZIKV) is a mosquito-borne pathogen classified by the World Health Organization
(WHO) as a public health emergency of international concern in 2016, and it is still identified …

[HTML][HTML] Zika virus capsid anchor forms cytotoxic amyloid-like fibrils

KU Saumya, K Gadhave, A Kumar, R Giri - Virology, 2021 - Elsevier
Capsid-anchor (CA) of Zika virus (ZIKV) is a small, single-pass transmembrane sequence
that separates the capsid (C) protein from downstream pre-membrane (PrM) protein. During …

Widespread amyloid aggregates formation by Zika virus proteins and peptides

R Giri, T Bhardwaj, SK Kapuganti, KU Saumya… - Protein …, 2023 - Wiley Online Library
Viral pathogenesis typically involves numerous molecular mechanisms. Protein aggregation
is a relatively unknown characteristic of viruses, despite the fact that viral proteins have been …

Computational methods to study intrinsically disordered proteins

P Kumar, A Bhardwaj, VN Uversky, T Tripathi… - Advances in protein …, 2022 - Elsevier
In the 21st century, evolving computational power has provided great help to understand,
build, and execute numerous ideas in almost every field. The improvements in …

Zika Virus Capsid Anchor Forms Cytotoxic Amyloid-like Fibrils

KU Saumya, K Gadhave, A Kumar, R Giri - bioRxiv, 2020 - biorxiv.org
Capsid-anchor (CA) of Zika virus (ZIKV) is a small, single-pass transmembrane sequence
that separates the capsid (C) protein from downstream pre-membrane (PrM) protein. During …

[图书][B] Virus-Host Cell Interactions Modulating the Pathogenesis of ZIKV In Vitro

IMN Bird - 2021 - search.proquest.com
Abstract The reemergence of Zika Virus (ZIKV) isolates that result in severe neuropathology
has elevated ZIKV into a major concern for global health following outbreaks in French …

Evolução in vitro do vírus Zika e seu impacto sobre a aptidão viral em diferentes modelos biológicos–in vitro e in vivo

VA Nascimento - 2021 - arca.fiocruz.br
As infecções ocasionadas por arbovírus representam sérios problemas de saúde pública
em regiões tropicais e subtropicais do planeta. No Brasil, além da circulação dos diferentes …

[引用][C] Host cell responses and protein-protein interactions in tick-borne encephalitis virus infection

V Breitkopf, M Johanna - 2021