Objective To deal with COVID‐19, various countries have made many efforts, including the
research and development of vaccines. The purpose of this manuscript was to summarize …

A reduced removal of dysfunctional mitochondria is common to aging and age-related
neurodegenerative pathologies such as Alzheimer's disease (AD). Strategies for treating …

Abstract The SARS-CoV-2 3CL protease is a critical drug target for small molecule COVID-
19 therapy, given its likely druggability and essentiality in the viral maturation and replication …

The Covid-19 Vaccine-Development Multiverse Penny Heaton comments on preliminary
findings from a trial of an mRNA vaccine against Covid-19, noting that the time from …

The value of in silico methods in drug development and evaluation has been demonstrated
repeatedly and convincingly. While their benefits are now unanimously recognized …

In late December 2019, a new coronavirus (CoV) called the severe acute respiratory
syndrome CoV 2 (SARS-CoV-2), which had not been detected in humans before, caused a …

Ceftazidime‐avibactam is a novel β‐lactam/β‐lactamase inhibitor combination for the
treatment of serious infections caused by resistant gram‐negative pathogens. Population …

The best arm identification problem in the multi-armed bandit setting is an excellent model of
many real-world decision-making problems, yet it fails to capture the fact that in the real …

Unlike artificial nanosystems, biological systems are ideally engineered to respond to their
environment. As such, natural molecular buffers ensure precise and quantitative delivery of …

In drug development, pharmacometric approaches consist in identifying via a model
selection (MS) process the model structure that best describes the data. However, making …