The subject of crystal engineering started in the 1970s with the study of topochemical
reactions in the solid state. A broad chemical definition of crystal engineering was published …

Pharmaceutical cocrystals belong to a sub-class of cocrystals wherein one of the
components is a drug molecule (or an active pharmaceutical ingredient, API) and the …

Cocrystals are an emerging class of crystalline materials composed of two or more different
molecules in the same crystal lattice that are physically connected by non-ionic and non …

Mechanochemistry is considered an alternative attractive greener approach to prepare
diverse molecular compounds and has become an important synthetic tool in different fields …

Recently, drug-drug cocrystal attracts more and more attention. It offers a low risk, low-cost
but high reward route to new and better medicines and could improve the physiochemical …

Isoniazid (INH) is a key drug ingredient in the fixed dose combination for the treatment of
tuberculosis (TB). INH is highly soluble in aqueous medium and also stable in pure form, but …

Andrographis paniculata (Burm. f.) Nees has been used as a traditional medicine in Asian
countries, especially China, India, Vietnam, Malaysia, and Indonesia. This herbaceous plant …

White spot lesions around orthodontic brackets are the major complication during fixed
orthodontic treatment. This study prepared orthodontic adhesives for promoting mineral …

Cocrystallization is a well-established technique to improve the solubility, bioavailability, and
stability of active pharmaceutical ingredients (APIs) but permeability and diffusion rate …

Cocrystallization has emerged over the past decade as an attractive technique for
modification of the physicochemical properties of compounds used as active pharmaceutical …