Latest advances of virology research using CRISPR/Cas9-based gene-editing technology and its application to vaccine development

M Teng, Y Yao, V Nair, J Luo - Viruses, 2021 - mdpi.com
In recent years, the CRISPR/Cas9-based gene-editing techniques have been well
developed and applied widely in several aspects of research in the biological sciences, in …

Post-genomic era in agriculture and veterinary science: Successful and proposed application of genetic targeting technologies

A Mazloum, M Karagyaur, R Chernyshev… - Frontiers in Veterinary …, 2023 - frontiersin.org
Gene editing tools have become an indispensable part of research into the fundamental
aspects of cell biology. With a vast body of literature having been generated based on next …

[HTML][HTML] ZDHHC22-mediated mTOR palmitoylation restrains breast cancer growth and endocrine therapy resistance

J Huang, J Li, J Tang, Y Wu, F Dai, Z Yi… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
Palmitoylation is essential for the classic hallmarks of cancers through regulating protein
stability and protein-protein interactions. ZDHHC22, as a well-known member of …

S-acylation of proteins of coronavirus and influenza virus: conservation of acylation sites in animal viruses and DHHC acyltransferases in their animal reservoirs

DA Abdulrahman, X Meng, M Veit - Pathogens, 2021 - mdpi.com
Recent pandemics of zoonotic origin were caused by members of coronavirus (CoV) and
influenza A (Flu A) viruses. Their glycoproteins (S in CoV, HA in Flu A) and ion channels (E …

[HTML][HTML] Lipid switches in the immunological synapse

G Griffiths, B Brügger, C Freund - Journal of Biological Chemistry, 2024 - Elsevier
Adaptive immune responses comprise the activation of T cells by peptide antigens that are
presented by proteins of the Major Histocompatibility Complex (MHC) on the surface of an …

Genetic determinants for virulence and adaptation of avian influenza viruses H9N2 and H5N8 subtypes in poultry and mammals

C Blaurock - 2021 - epub.ub.uni-greifswald.de
LPAIV H9N2 and HPAIV H5N8 clade 2.3. 4.4 viruses have been frequently isolated from
domestic and wild birds in Germany and they are endemic in poultry worldwide. H9N2 is …