Chrysin: Sources, beneficial pharmacological activities, and molecular mechanism of action

R Mani, V Natesan - Phytochemistry, 2018 - Elsevier
In recent years, public and scientific interest in plant flavonoids has tremendously increased
because of their postulated health benefits. This review was mainly focuses on the flavone …

An overview on immunoregulatory and anti-inflammatory properties of chrysin and flavonoids substances

M Zeinali, SA Rezaee, H Hosseinzadeh - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Inflammation and the pro-inflammatory cytokines are associated with numerous chronic
diseases. Studies suggest that flavonoids, plant polyphenolic compound derivatives from …

[HTML][HTML] Molecular mechanism-based therapeutic properties of honey

M Talebi, M Talebi, T Farkhondeh… - Biomedicine & …, 2020 - Elsevier
Honey and its phenolic compounds specifically chrysin are focused as nutritional
supplements and likewise as valued phytochemicals, nutraceuticals, and …

[HTML][HTML] An updated review on the versatile role of chrysin in neurological diseases: Chemistry, pharmacology, and drug delivery approaches

M Talebi, M Talebi, T Farkhondeh… - Biomedicine & …, 2021 - Elsevier
Neurological diseases are responsible for a large number of morbidities and mortalities in
the world. Flavonoids are phytochemicals that possess various health-promoting impacts …

Proinflammatory pathways: the modulation by flavonoids

D Ribeiro, M Freitas, JLFC Lima… - Medicinal research …, 2015 - Wiley Online Library
Inflammation is a natural, carefully orchestrated response of the organism to tissue damage,
involving various signaling systems and the recruitment of inflammatory cells. These cells …

Preparation and characterization of PLGA-PEG-PLGA polymeric nanoparticles for co-delivery of 5-Fluorouracil and Chrysin

S Khaledi, S Jafari, S Hamidi, O Molavi… - Journal of Biomaterials …, 2020 - Taylor & Francis
Despite significant advances in cancer therapy, chemotherapeutic agents are still the main
types of drugs used to treat cancer patients. 5-Fluorouracil (5-FU) is the first-line treatment in …

The immunomodulatory effects of honey and associated flavonoids in cancer

RJ Masad, SM Haneefa, YA Mohamed, A Al-Sbiei… - Nutrients, 2021 - mdpi.com
Honey has exerted a high impact in the field of alternative medicine over many centuries. In
addition to its wound healing, anti-microbial and antioxidant properties, several lines of …

Phytochemical-loaded mesoporous silica nanoparticles for nose-to-brain olfactory drug delivery

S Lungare, K Hallam, RKS Badhan - International journal of pharmaceutics, 2016 - Elsevier
Central nervous system (CNS) drug delivery is often hampered due to the insidious nature of
the blood-brain barrier (BBB). Nose-to-brain delivery via olfactory pathways have become a …

Chrysin attenuates atopic dermatitis by suppressing inflammation of keratinocytes

JK Choi, YH Jang, S Lee, SR Lee, YA Choi… - Food and Chemical …, 2017 - Elsevier
We previously reported the inhibitory effect of chrysin, a natural flavonoid plentifully
contained in propolis, vegetables and fruits, on the mast cell-mediated allergic reaction. In …

Dimethyl fumarate attenuates experimental autoimmune neuritis through the nuclear factor erythroid-derived 2-related factor 2/hemoxygenase-1 pathway by altering …

R Han, J Xiao, H Zhai, J Hao - Journal of neuroinflammation, 2016 - Springer
Abstract Background Guillain–Barré syndrome (GBS) is an acute, post-infectious, immune-
mediated, demyelinating disease of peripheral nerves and nerve roots. Dimethyl fumarate …