Perineuronal nets (PNNs) are extracellular matrix (ECM) chondroitin sulfate proteoglycan
(CSPG)-containing structures that surround the soma and dendrites of various mammalian …

Collagen hydrogels are among​ the most well-studied platforms for drug delivery and in situ
tissue engineering, thanks to their low cost, low immunogenicity, versatility, biocompatibility …

Cells encode information in the sequence of biopolymers, such as nucleic acids, proteins,
and glycans. Although glycans are essential to all living organisms, surprisingly little is …

The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Regeneration is the process of replacing/restoring a damaged cell/tissue/organ to its full
function and is limited respecting complexity of specific organ structures and the level of …

Non-healing, chronic wounds place a huge burden on healthcare systems as well as
individual patients. These chronic wounds especially diabetic wounds will ultimately lead to …

Alginates have become an extremely important family of polysaccharides because of their
utility in preparing hydrogels at mild pH and temperature conditions, suitable for sensitive …

Sulfation is a dynamic and complex posttranslational modification process. It can occur at
various positions within the glycosaminoglycan (GAG) backbone and modulates …

In antibody responses, mutated germinal center B (BGC) cells are positively selected for
reentry or differentiation. As the products from GCs, memory B cells and antibody-secreting …

The development of biomaterials for cardiac tissue engineering (CTE) is challenging,
primarily owing to the requirement of achieving a surface with favourable characteristics that …