Mitochondria are critical cellular organelles for energy generation and are now also
recognized as playing important roles in cellular signaling. Their central role in energy …

The liver is not only involved in metabolism and detoxification, but also participate in innate
immune function and thus exposed to frequent target Thus, they are the frequent target of …

Mother-infant contact has a critical role on brain development and behavior. Experiencing
early-life adversities (such as maternal separation stress or MS in rodents) results in …

Hepatotoxicity induced by antituberculosis drugs is a serious adverse reaction with
significant morbidity and even, rarely, mortality. This form of toxicity potentially impacts the …

Isoniazid (INH) is among the most important anti-tuberculosis agents widely prescribed.
However, its clinical use is restricted due to its severe side effects associated with …

An increasing number of commonly prescribed drugs are known to interfere with
mitochondrial function, which is associated with almost half of all Food and Drug …

High blood pressure, or “hypertension,” is associated with high levels of oxidative stress in
the paraventricular nucleus of the hypothalamus. While pomegranate extract is a known …

Isoniazid (INH) is a synthetic anti-mycobacterial agent used to treat active or latent
tuberculosis (TB). INH has been in clinical use for nearly 70 years and remains broadly …

Parkinson's disease (PD) is one of the most common neurodegenerative disorders and is
characterized by loss of dopaminergic neurons in the substantia nigra (SN). Although the …

With the ageing population globally, tuberculosis (TB) in older people becomes a major
clinical and public health challenge. In many Asian countries, especially those located in the …