Plant sugars are crucial players in the oxidative challenge during abiotic stress: extending the traditional concept

ELS Keunen, D Peshev, J Vangronsveld… - Plant, cell & …, 2013 - Wiley Online Library
Plants suffering from abiotic stress are commonly facing an enhanced accumulation of
reactive oxygen species (ROS) with damaging as well as signalling effects at organellar and …

Class III peroxidase: an indispensable enzyme for biotic/abiotic stress tolerance and a potent candidate for crop improvement

M Kidwai, IZ Ahmad, D Chakrabarty - Plant cell reports, 2020 - Springer
Class III peroxidases are secretory enzymes which belong to a ubiquitous multigene family
in higher plants and have been identified to play role in a broad range of physiological and …

A microbial supply chain for production of the anti-cancer drug vinblastine

J Zhang, LG Hansen, O Gudich, K Viehrig… - Nature, 2022 - nature.com
Monoterpene indole alkaloids (MIAs) are a diverse family of complex plant secondary
metabolites with many medicinal properties, including the essential anti-cancer therapeutics …

Single-cell multi-omics in the medicinal plant Catharanthus roseus

C Li, JC Wood, AH Vu, JP Hamilton… - Nature Chemical …, 2023 - nature.com
Advances in omics technologies now permit the generation of highly contiguous genome
assemblies, detection of transcripts and metabolites at the level of single cells and high …

Single-cell RNA sequencing provides a high-resolution roadmap for understanding the multicellular compartmentation of specialized metabolism

S Sun, X Shen, Y Li, Y Li, S Wang, R Li, H Zhang… - Nature plants, 2023 - nature.com
Monoterpenoid indole alkaloids (MIAs) are among the most diverse specialized metabolites
in plants and are of great pharmaceutical importance. We leveraged single-cell …

Class III peroxidases in plant defence reactions

L Almagro, LV Gómez Ros… - Journal of …, 2009 - academic.oup.com
When plants are attacked by pathogens, they defend themselves with an arsenal of defence
mechanisms, both passive and active. The active defence responses, which require de novo …

Indole Alkaloids from Catharanthus roseus: Bioproduction and Their Effect on Human Health

L Almagro, F Fernández-Pérez, MA Pedreño - Molecules, 2015 - mdpi.com
Catharanthus roseus is a medicinal plant belonging to the family Apocynaceae which
produces terpenoid indole alkaloids (TIAs) of high medicinal importance. Indeed, a number …

Roles of cell wall peroxidases in plant development

E Francoz, P Ranocha, H Nguyen-Kim, E Jamet… - Phytochemistry, 2015 - Elsevier
Abstract Class III peroxidases (CIII Prxs) are plant specific proteins. Based on in silico
prediction and experimental evidence, they are mainly considered as cell wall localized …

The Transcription Factor CrWRKY1 Positively Regulates the Terpenoid Indole Alkaloid Biosynthesis in Catharanthus roseus

N Suttipanta, S Pattanaik, M Kulshrestha… - Plant …, 2011 - academic.oup.com
Catharanthus roseus produces a large array of terpenoid indole alkaloids (TIAs) that are an
important source of natural or semisynthetic anticancer drugs. The biosynthesis of TIAs is …

Specific functions of individual class III peroxidase genes

C Cosio, C Dunand - Journal of experimental botany, 2009 - academic.oup.com
In higher plants, class III peroxidases exist as large multigene families (eg 73 genes in
Arabidopsis thaliana). The diversity of processes catalysed by peroxidases as well as the …