SARS coronavirus 2: from genome to infectome

M Rastogi, N Pandey, A Shukla, SK Singh - Respiratory research, 2020 - Springer
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) belongs to the group of
Betacoronaviruses. The SARS-CoV-2 is closely related to SARS-CoV-1 and probably …

COVID-19-driven endothelial damage: complement, HIF-1, and ABL2 are potential pathways of damage and targets for cure

M Marchetti - Annals of hematology, 2020 - Springer
COVID-19 pandemia is a major health emergency causing hundreds of deaths worldwide.
The high reported morbidity has been related to hypoxia and inflammation leading to …

Rationale for targeting complement in COVID‐19

A Polycarpou, M Howard, CA Farrar… - EMBO molecular …, 2020 - embopress.org
A novel coronavirus, SARS‐CoV‐2, has recently emerged in China and spread
internationally, posing a health emergency to the global community. COVID‐19 caused by …

[HTML][HTML] Lymphopenic community acquired pneumonia as signature of severe COVID-19 infection

JF Bermejo-Martin, R Almansa, R Menendez… - The Journal of …, 2020 - ncbi.nlm.nih.gov
As recently commented by Tang and colleagues in this Journal, the novel Coronavirus
emerged at the end of 2019 from Wuhan has already spread beyond China [1], which led …

Lymphopenia in sepsis—an acquired immunodeficiency?

S Finfer, B Venkatesh, RS Hotchkiss… - Immunology and Cell …, 2023 - Wiley Online Library
Sepsis is a global health priority, yet effective host‐directed targeted therapies have not
been identified outside of the setting of coronavirus disease 2019 (COVID‐19) …

[HTML][HTML] Immune response to SARS-CoV-2 variants: A focus on severity, susceptibility, and preexisting immunity

E Alefishat, HF Jelinek, M Mousa, GK Tay… - Journal of Infection and …, 2022 - Elsevier
The heterogeneous phenotypes among patients with coronavirus disease 2019 (COVID-19)
has drawn worldwide attention, especially those with severe symptoms without comorbid …

Lymphopenia is associated with poor outcomes of patients with community-acquired pneumonia and sepsis

C Cilloniz, HJ Peroni, A Gabarrús… - Open Forum …, 2021 - academic.oup.com
Background Lymphopenia is a marker of poor prognosis in patients with community-
acquired pneumonia (CAP), yet its impact on outcomes in patients with CAP and sepsis …

[HTML][HTML] Atypical lymphocytes in peripheral blood of patients with COVID‐19

SE Weinberg, A Behdad, P Ji - British journal of haematology, 2020 - ncbi.nlm.nih.gov
2. Wu Z, McGoogan JM. Characteristics of and important lessons from the coronavirus
disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the …

Understanding the host in the management of pneumonia. An official American Thoracic Society workshop report

CS Dela Cruz, SE Evans, MI Restrepo… - Annals of the …, 2021 - atsjournals.org
Pneumonia causes a significant burden of disease worldwide. Although all populations are
at risk of pneumonia, those at extremes of age and those with immunosuppressive …

Cellular and molecular effects of SARS-CoV-2 linking lung infection to the brain

L Francistiová, A Klepe, G Curley, K Gulya… - Frontiers in …, 2021 - frontiersin.org
In December 2019, a new viral disease emerged and quickly spread all around the world. In
March 2020, the COVID-19 outbreak was classified as a global pandemic and by June …