Adverse obstetric outcomes after local treatment for cervical preinvasive and early invasive disease according to cone depth: systematic review and meta-analysis

M Kyrgiou, A Athanasiou, M Paraskevaidi, A Mitra… - bmj, 2016 - bmj.com
Objective To assess the effect of treatment for cervical intraepithelial neoplasia (CIN) on
obstetric outcomes and to correlate this with cone depth and comparison group used …

Clinical course of untreated cervical intraepithelial neoplasia grade 2 under active surveillance: systematic review and meta-analysis

K Tainio, A Athanasiou, KAO Tikkinen, R Aaltonen… - bmj, 2018 - bmj.com
Objective To estimate the regression, persistence, and progression of untreated cervical
intraepithelial neoplasia grade 2 (CIN2) lesions managed conservatively as well as …

Incomplete excision of cervical precancer as a predictor of treatment failure: a systematic review and meta-analysis

M Arbyn, CWE Redman, F Verdoodt, M Kyrgiou… - The Lancet …, 2017 - thelancet.com
Background Incomplete excision of cervical precancer is associated with therapeutic failure
and is therefore considered as a quality indicator of clinical practice. Conversely, the risk of …

The vaginal microbiota, human papillomavirus infection and cervical intraepithelial neoplasia: what do we know and where are we going next?

A Mitra, DA MacIntyre, JR Marchesi, YS Lee… - Microbiome, 2016 - Springer
The vaginal microbiota plays a significant role in health and disease of the female
reproductive tract. Next-generation sequencing techniques based upon the analysis of …

American Cancer Society, American Society for Colposcopy and Cervical Pathology, and American Society for Clinical Pathology screening guidelines for the …

D Saslow, D Solomon, HW Lawson… - American journal of …, 2012 - academic.oup.com
An update to the American Cancer Society (ACS) guideline regarding screening for the early
detection of cervical precancerous lesions and cancer is presented. The guidelines are …

Screening for cervical cancer: US Preventive Services Task Force recommendation statement

VA Moyer… - Annals of internal …, 2012 - acpjournals.org
This article has been corrected. The original version (PDF) is appended to this article as a
supplement. Description: Update of the 2003 US Preventive Services Task Force (USPSTF) …

Does the vaginal microbiota play a role in the development of cervical cancer?

M Kyrgiou, A Mitra, AB Moscicki - Translational Research, 2017 - Elsevier
Persistent infection with oncogenic human papillomavirus (HPV) is necessary but not
sufficient for the development of cervical cancer. The factors promoting persistence as well …

Clinical implications of (epi) genetic changes in HPV-induced cervical precancerous lesions

RDM Steenbergen, PJF Snijders… - Nature Reviews …, 2014 - nature.com
Infection of cervical epithelium with high-risk human papilloma virus (hrHPV) might result in
productive or transforming cervical intraepithelial neoplasia (CIN) lesions, the morphology of …

Efficacy of human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine against cervical infection and precancer caused by oncogenic HPV types (PATRICIA): final …

J Paavonen, P Naud, J Salmerón, CM Wheeler… - The Lancet, 2009 - thelancet.com
Background The human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine was
immunogenic, generally well tolerated, and effective against HPV-16 or HPV-18 infections …

Efficacy of human papillomavirus testing for the detection of invasive cervical cancers and cervical intraepithelial neoplasia: a randomised controlled trial

G Ronco, P Giorgi-Rossi, F Carozzi, M Confortini… - The lancet …, 2010 - thelancet.com
Background Human papillomavirus (HPV) testing is known to be more sensitive, but less
specific than cytology for detecting cervical intraepithelial neoplasia (CIN). We assessed the …