Resistance mechanisms to anti-angiogenic therapies in cancer

Y Haibe, M Kreidieh, H El Hajj, I Khalifeh… - Frontiers in …, 2020 - frontiersin.org
Tumor growth and metastasis rely on tumor vascular network for the adequate supply of
oxygen and nutrients. Tumor angiogenesis relies on a highly complex program of growth …

Resistance to anti-angiogenic therapy in cancer—alterations to anti-VEGF pathway

Y Itatani, K Kawada, T Yamamoto, Y Sakai - International journal of …, 2018 - mdpi.com
Anti-angiogenic therapy is one of the promising strategies for many types of solid cancers.
Bevacizumab (Avastin), a recombinant humanized monoclonal antibody of vascular …

Diet and colorectal cancer risk in Asia-a systematic review

S Azeem, SW Gillani, A Siddiqui… - Asian Pacific journal …, 2015 - koreascience.kr
Diet is one of the major factors that can exert a majorly influence on colorectal cancer risk.
This systematic review aimed to find correlations between various diet types, food or …

Are markers of systemic inflammation good prognostic indicators in colorectal cancer?

S Rossi, M Basso, A Strippoli, G Schinzari… - Clinical colorectal …, 2017 - Elsevier
Systemic inflammation has been proved to play a crucial role in promoting cancer
progression and metastasis in many cancer types, including colorectal cancer (CRC). The …

Cellular signaling in the hypoxic cancer microenvironment: Implications for drug resistance and therapeutic targeting

HA Bakshi, M Mkhael, HL Faruck, AU Khan… - Cellular …, 2023 - Elsevier
The rewiring of cellular metabolism is a defining characteristic of cancer, as tumor cells
adapt to acquire essential nutrients from a nutrient-poor environment to sustain their viability …

Myeloid-derived suppressor cells in multiple myeloma: pre-clinical research and translational opportunities

C Botta, A Gullà, P Correale, P Tagliaferri… - Frontiers in …, 2014 - frontiersin.org
Immunosuppressive cells have been reported to play an important role in tumor-progression
mainly because of their capability to promote immune-escape, angiogenesis, and …

Mean platelet volume as a prognostic marker in metastatic colorectal cancer patients treated with bevacizumab-combined chemotherapy

T Tunce, A Ozgun, L Emirzeoglu, S Celik… - Asian Pacific Journal …, 2014 - koreascience.kr
Background: Recent studies have revealed a prognostic impact of the MPV (mean platelet
volume)/platelet count ratio in terms of survival in advanced non-small cell lung cancer …

[HTML][HTML] A new inflammatory prognostic index, based on C-reactive protein, the neutrophil to lymphocyte ratio and serum albumin is useful for predicting prognosis in …

N Dirican, A Dirican, C Anar, S Atalay… - Asian Pacific journal …, 2016 - ncbi.nlm.nih.gov
Purpose: We aimed to establish an inflammatory prognostic index (IPI) in early and
advanced non-small cell lung cancer (NSCLC) patients based on hematologic and …

Immune-related genes to dominate neutrophil-lymphocyte ratio (NLR) associated with survival of cetuximab treatment in metastatic colorectal cancer

Y Sunakawa, D Yang, S Cao, W Zhang, M Moran… - Clinical colorectal …, 2018 - Elsevier
Background Few clinical studies have investigated the association between neutrophil-
lymphocyte ratio (NLR) and treatment with cetuximab-based chemotherapy in metastatic …

[HTML][HTML] Laboratory parameters are possible prognostic markers in patients with advanced-stage NSCLC treated with bevacizumab plus chemotherapy

M Svaton, J Blazek, G Krakorova, M Buresova… - Journal of …, 2021 - ncbi.nlm.nih.gov
Purpose: To investigate potential associations between selected laboratory markers (CRP,
LDH, albumin, sodium, hemoglobin, neutrophils, and neutrophils/lymphocytes ratio [NLR]) …