Apnea of prematurity: from cause to treatment

J Zhao, F Gonzalez, D Mu - European journal of pediatrics, 2011 - Springer
Apnea of prematurity (AOP) is a common problem affecting premature infants, likely
secondary to a “physiologic” immaturity of respiratory control that may be exacerbated by …

Esophageal impedance monitoring for gastroesophageal reflux

HM Mousa, R Rosen, FW Woodley, M Orsi… - Journal of pediatric …, 2011 - journals.lww.com
Dual pH-multichannel intraluminal impedance (pH-MII) is a sensitive tool for evaluating
overall gastroesophageal reflux disease, and particularly for permitting detection of nonacid …

Multicenter, double-blind, randomized, placebo-controlled trial assessing the efficacy and safety of proton pump inhibitor lansoprazole in infants with symptoms of …

SR Orenstein, E Hassall, W Furmaga-Jablonska… - The Journal of …, 2009 - Elsevier
OBJECTIVE: To assess the efficacy and safety of lansoprazole in treating infants with
symptoms attributed to gastroesophageal reflux disease (GERD) that are persisting despite …

Proton pump inhibitor use in infants: FDA reviewer experience

IL Chen, WY Gao, AP Johnson, A Niak… - Journal of pediatric …, 2012 - journals.lww.com
Abstract The Food and Drug Administration has completed its review of 4 clinical trials
evaluating the use of proton pump inhibitors (PPIs) in infants (ages 1 month to< 12 months) …

Measuring response in the gastrointestinal tract in systemic sclerosis

D Khanna, V Nagaraja, H Gladue, W Chey… - Current opinion in …, 2013 - journals.lww.com
Measuring response in the gastrointestinal tract in systemic... : Current Opinion in
Rheumatology Measuring response in the gastrointestinal tract in systemic sclerosis …

Role of the multichannel intraluminal impedance technique in infants and children

MP van Wijk, MA Benninga… - Journal of pediatric …, 2009 - journals.lww.com
Recently, multichannel intraluminal impedance (MII) was added to the repertoire of tests
available to study esophageal (patho) physiology in children. MII has since been used in 2 …

Over-prescription of acid-suppressing medications in infants: how it came about, why it's wrong, and what to do about it

E Hassall - The Journal of pediatrics, 2012 - jpeds.com
(PPIs) were initially shown to be effective, safe, and well-tolerated for the short-term
treatment of gastroesophageal reflux disease (GERD) in children over 1 year of age 1; …

Pepsin in saliva as a biomarker for oropharyngeal reflux compared with 24‐hour esophageal impedance/pH monitoring in pediatric patients

JE Fortunato, RB D'Agostino Jr… - Neurogastroenterology …, 2017 - Wiley Online Library
Background Pepsin in saliva is a proposed biomarker for oropharyngeal reflux. Pepsin may
be prevalent in saliva from subjects with gastro‐esophageal reflux and may correlate with …

Use of anti-reflux medications in infants under 1 year of age: a retrospective drug utilization study using national prescription reimbursement data

D O'Reilly, R Conway, L O'Connor… - European journal of …, 2020 - Springer
Non-specific symptoms such as irritability, vomiting, and back arching during the infant
period are often attributed to gastroesophageal reflux. While numerous studies have shown …

Infant gastroesophageal reflux disease management consensus

Y Vandenplas, M Orsi, M Benninga… - Acta …, 2024 - Wiley Online Library
Aim Infant gastroesophageal reflux is mostly benign; however, when associated with
complications like failure to thrive, it may be indicative of gastroesophageal reflux disease …