Among age-related diseases, cardiovascular and cerebrovascular diseases are major
causes of death. Vascular dysfunction is a key characteristic of these diseases wherein age …

Accumulating evidence suggests that central blood pressure (BP) may reflect the
hemodynamic stress on target organs more accurately than brachial BP. A systematic review …

Background: By contrast with other southern European people, north Portuguese population
registers an especially high prevalence of hypertension and stroke incidence. We designed …

Background Alterations in the anatomic and biomechanical properties of the ascending
aorta (AAo) can give rise to various vascular pathologies. The aim of the current study is to …

Arterial stiffness index (ASI) is a non-invasive measure of arterial stiffness using infra-red
finger sensors (photoplethysmography). It is a well-suited measure for large populations as it …

The genetic contribution of blood pressure and heart rate (HR) varied widely between
studies. Demographic factors such as ethnicity, age and/or sex might explain some of the …

Background Obstructive sleep apnoea (OSA) is one of the major sources of the excessive
daily sleepiness, cognitive dysfunction, and it increases cardiovascular morbidity and …

The first Hungarian Twin Registry was established in Budapest in 1970 through the
mandatory reporting of multiple-births. In the 1980s a second, volunteer adult registry was …

Rationale Obesity, blood pressure and arterial stiffness are heritable traits interconnected to
each other but their possible common genetic and environmental etiologies are unknown …

Since our last report on the voluntary Hungarian Twin Registry (HTR) in 2012, the number of
pairs or multiplets included increased from 310 to 1044. Efforts to turn the registry into a …