Glycine and glycine receptor signaling in hippocampal neurons: diversity, function and regulation
TL Xu, N Gong - Progress in neurobiology, 2010 - Elsevier
Glycine is a primary inhibitory neurotransmitter in the spinal cord and brainstem. It acts at
glycine receptor (GlyR)-chloride channels, as well as a co-agonist of NMDA receptors …
glycine receptor (GlyR)-chloride channels, as well as a co-agonist of NMDA receptors …
Glycine receptors and brain development
Glycine receptors (GlyRs) are ligand-gated chloride ion channels that mediate fast inhibitory
neurotransmission in the spinal cord and the brainstem. There, they are mainly involved in …
neurotransmission in the spinal cord and the brainstem. There, they are mainly involved in …
Distributed genetic architecture across the hippocampal formation implies common neuropathology across brain disorders
Despite its major role in complex human functions across the lifespan, most notably
navigation, learning and memory, much of the genetic architecture of the hippocampal …
navigation, learning and memory, much of the genetic architecture of the hippocampal …
D-Serine and glycine differentially control neurotransmission during visual cortex critical period
N-methyl-D-aspartate receptors (NMDARs) play a central role in synaptic plasticity. Their
activation requires the binding of both glutamate and d-serine or glycine as co-agonist. The …
activation requires the binding of both glutamate and d-serine or glycine as co-agonist. The …
Role of glycine receptors in glycine-induced LTD in hippocampal CA1 pyramidal neurons
RQ Chen, SH Wang, W Yao, JJ Wang, F Ji… - …, 2011 - nature.com
Glycine in the hippocampus can exert its effect on both synaptic NMDA receptors (NMDARs)
and extrasynaptic functional glycine receptors (GlyRs) via distinct binding sites. Previous …
and extrasynaptic functional glycine receptors (GlyRs) via distinct binding sites. Previous …
Glycine receptors control the generation of projection neurons in the developing cerebral cortex
A Avila, PM Vidal, S Tielens, G Morelli… - Cell Death & …, 2014 - nature.com
The development of the cerebral cortex requires coordinated regulation of proliferation,
specification, migration and differentiation of cortical progenitors into functionally integrated …
specification, migration and differentiation of cortical progenitors into functionally integrated …
Glycinergic inhibition in the hippocampus
Glycine and GABA are the two main inhibitory neurotransmitters in the central nervous
system (CNS). While GABA receptors in the hippocampus have been studied in great detail …
system (CNS). While GABA receptors in the hippocampus have been studied in great detail …
GABAA Receptor and Glycine Receptor Activation by Paracrine/Autocrine Release of Endogenous Agonists: More Than a Simple Communication Pathway
H Le-Corronc, JM Rigo, P Branchereau… - Molecular …, 2011 - Springer
It is a common and widely accepted assumption that glycine and GABA are the main
inhibitory transmitters in the central nervous system (CNS). But, in the past 20 years, several …
inhibitory transmitters in the central nervous system (CNS). But, in the past 20 years, several …
Sarcosine preconditioning induces ischemic tolerance against global cerebral ischemia
Brain ischemic tolerance is an endogenous protective mechanism activated by a
preconditioning stimulus that is closely related to N-methyl-d-aspartate receptor (NMDAR) …
preconditioning stimulus that is closely related to N-methyl-d-aspartate receptor (NMDAR) …
Glycine receptors support excitatory neurotransmitter release in developing mouse visual cortex
PA Kunz, AC Burette, RJ Weinberg… - The Journal of …, 2012 - Wiley Online Library
Key points• Cortical glycine receptors (GlyRs) flux chloride based on a local chloride
gradient set by chloride transporters; this gradient changes with age.• In acute slices from …
gradient set by chloride transporters; this gradient changes with age.• In acute slices from …