The application of microfabrication to the development of biomedical implants has produced
a new generation of miniaturized technology for assisting treatment and research …

Long-term potentiation (LTP) of synaptic transmission is a widely accepted model that
attempts to link synaptic plasticity with memory. LTP models are also now used in order to …

The promise of advanced neuroprosthetic systems to significantly improve the quality of life
for a segment of the deaf, blind, or paralyzed population hinges on the development of an …

We present a micromachined 252-channel ECoG (electrocorticogram)-electrode array,
which is made of a thin polyimide foil substrate enclosing sputtered platinum electrode sites …

The characteristics and mechanisms of synchronized firing in developing networks of
cultured cortical neurons were studied using multisite recording through planar electrode …

In order to be used as a material for neural prostheses, polyimide has to withstand the body
environment over years. To obtain more information about the long-term stability of this …

Spatiotemporally coordinated activity of neural networks is crucial for brain functioning. To
understand the basis of physiological information processing and pathological states …

Complementary semiconductor-metal-oxide (CMOS) technology is a very powerful
technology that can be more or less directly interfaced to electrogenic cells, like heart or …

The study of intracellular communication requires devices that can not only monitor the
bioelectric activity, but also control and observe the biochemical environment at the cellular …

Precise control of the architecture of multiple cells in culture and in vivo via precise
engineering of the material surface properties is described as cell patterning. Substrate …