Systemic inflammation can be triggered by infection, surgery, trauma or burns. During
systemic inflammation, an overshooting immune response induces tissue damage resulting …

Objective: The use of procalcitonin (ProCT) as a marker of several clinical conditions, in
particular, systemic inflammation, infection, and sepsis, will be clarified, and its current …

Calcitonin (CT) is a hormone that received its name because of its secretion in response to
induced hypercalcemia and its hypocalcemic effect (1). It was shown to originate from the …

The worldwide yearly mortality from sepsis is substantial, greater than that of cancer of the
lung and breast combined. Moreover, its incidence is increasing, and its response to therapy …

Circulating levels of calcitonin precursors (CTpr), including procalcitonin (ProCT), increase
up to several thousand-fold in human sepsis, and immunoneutralization improves survival in …

Objective: To explore the roles of peripheral blood mononuclear cells (PBMCs) and PBMC-
derived macrophages in sepsis-related increased procalcitonin and calcitonin gene-related …

Over the past two decades, a convergence of basic and clinical evidence has established
the neuropeptide calcitonin-gene-related peptide (CGRP) as a key player in migraine …

This review aims to provide physicians with an overview of the potential of procalcitonin to
guide antibiotic therapy in respiratory tract infections and in sepsis. Knowledge of the …

Human adipose tissue is a contributor to inflammation-and sepsis-induced elevation of
serum procalcitonin (ProCT). Several calcitonin (CT) peptides, including ProCT, CT gene …

Procalcitonin is a surrogate biomarker for estimating the likelihood of a bacterial infection.
Procalcitonin-guided initiation and termination of antibiotic therapy is a novel approach …