[HTML][HTML] Trimethylamine N-oxide (TMAO) in human health

P Gatarek, J Kaluzna-Czaplinska - EXCLI journal, 2021 - ncbi.nlm.nih.gov
Due to numerous links between trimethylamine-N-oxide (TMAO) and various disorders and
diseases, this topic is very popular and is often taken up by researchers. TMAO is a low …

Trimethylamine N-oxide and prognosis in acute heart failure

T Suzuki, LM Heaney, SS Bhandari, DJL Jones, LL Ng - Heart, 2016 - heart.bmj.com
Objective Acute heart failure (AHF) is associated with high mortality and morbidity.
Trimethylamine N-oxide (TMAO), a gut-derived metabolite, has reported association with …

Depletion of microbiome-derived molecules in the host using Clostridium genetics

CJ Guo, BM Allen, KJ Hiam, D Dodd, W Van Treuren… - Science, 2019 - science.org
INTRODUCTION The gut microbiota produce hundreds of molecules that are present at high
concentrations in circulation and whose levels vary widely among humans. These …

Assessment of gut microbiota fecal metabolites by chromatographic targeted approaches

J Fiori, S Turroni, M Candela, R Gotti - Journal of Pharmaceutical and …, 2020 - Elsevier
Gut microbiota, the specific microbial community of the gastrointestinal tract, by means of the
production of microbial metabolites provides the host with several functions affecting …

Metabolic products of the intestinal microbiome and extremes of atherosclerosis

C Bogiatzi, G Gloor, E Allen-Vercoe, G Reid, RG Wong… - Atherosclerosis, 2018 - Elsevier
Background and aims There is increasing awareness that the intestinal microbiome plays an
important role in human health. We investigated its role in the burden of carotid …

Trimethylamine N-oxide and Risk Stratification after Acute Myocardial Infarction

T Suzuki, LM Heaney, DJL Jones, LL Ng - Clinical chemistry, 2017 - academic.oup.com
BACKGROUND Risk stratification in acute myocardial infarction (MI) remains a clinical
challenge. Trimethylamine N-oxide (TMAO), a gut-derived metabolite, was investigated for …

Balancing the Equation: A Natural History of Trimethylamine and Trimethylamine-N-oxide

RL Loo, Q Chan, JK Nicholson… - Journal of Proteome …, 2022 - ACS Publications
Trimethylamine (TMA) and its N-oxide (TMAO) are ubiquitous in prokaryote and eukaryote
organisms as well as in the environment, reflecting their fundamental importance in …

TMAO is associated with mortality: impact of modestly impaired renal function

EG Gruppen, E Garcia, MA Connelly, EJ Jeyarajah… - Scientific reports, 2017 - nature.com
Abstract Trimethylamine-N-Oxide (TMAO) is a microbiome-related metabolite that is cleared
by the kidney and linked to renal function. We explored the relationship between TMAO and …

Association with outcomes and response to treatment of trimethylamine N‐oxide in heart failure: results from BIOSTAT‐CHF

T Suzuki, Y Yazaki, AA Voors… - European journal of …, 2019 - Wiley Online Library
Aims Association of elevated circulating levels of trimethylamine N‐oxide (TMAO) with
adverse outcomes in patients with heart failure (HF) has been described. However …

Gut microbial taxa as potential predictive biomarkers for acute coronary syndrome and post-STEMI cardiovascular events

J Gao, KT Yan, JX Wang, J Dou, J Wang, M Ren… - Scientific reports, 2020 - nature.com
Plasma trimethylamine N-oxide (TMAO) is associated with coronary atherosclerotic plaque
and cardiovascular disease risk, but associations between gut microbes in acute coronary …