Methotrexate is used in the treatment of many malignancies, rheumatological diseases, and
inflammatory bowel disease. Toxicity from use is associated with severe morbidity and …

Methotrexate (MTX) toxicity varies depending on factors such as dosing frequency (acute or
repeated), dosage (low or high) and the administration route (oral, parenteral or intrathecal) …

Background: Methotrexate is a folate analog prescribed for varying disease with weekly
administration as opposed to daily. Dosing errors can prove clinically significant and …

Methotrexate is an antimetabolite drug with antineoplastic and immunomodulatory
properties, useful as an antineoplastic agent in various haematological and solid tumours …

The aim of this study was the establishment of a UHPLC-QqQ-MS/MS method to determine
methotrexate in postmortem biological samples and quantify the postmortem distribution of …

Editor's Note: Annals has partnered with EM: RAP, enabling our readers without
subscriptions to EM: RAP to enjoy their commentary on Annals publications. This article did …

The aim of this study was the establishment of a UHPLC-QqQ-MS/MS method to determine
methotrexate in postmortem biological samples and quantify the postmortem distribution of …

Purpose To evaluate the impact of FDA's 2013 zolpidem Drug Safety Communications
(DSCs), which recommended lowering the initial dose to mitigate drowsiness, on national …

Abstract Purpose of Review Our primary aim was to create a succinct yet thorough evidence-
based review of the pharmacokinetics, pharmacodynamics, clinical presentation, evaluation …

Abstract Background and Objectives: Pediatric ingestions of amphetamines used in the
treatment of Attention Deficit Hyperactivity Disorder (ADHD) are on the rise. Little data …