Papaverine: a miraculous alkaloid from opium and its multimedicinal application

S Ashrafi, S Alam, A Sultana, A Raj, NU Emon, FT Richi… - Molecules, 2023 - mdpi.com
The pharmacological actions of benzylisoquinoline alkaloids are quite substantial, and have
recently attracted much attention. One of the principle benzylisoquinoline alkaloids has been …

Benzylisoquinoline alkaloid biosynthesis in opium poppy: an update

A Singh, IM Menéndez-Perdomo, PJ Facchini - Phytochemistry Reviews, 2019 - Springer
For nearly eight millennia, opium poppy (Papaver somniferum) has been bred and cultivated
for therapeutic purposes. The medicinal properties of the plant are conferred by specialized …

Integrated omics analysis of specialized metabolism in medicinal plants

A Rai, K Saito, M Yamazaki - The Plant Journal, 2017 - Wiley Online Library
Medicinal plants are a rich source of highly diverse specialized metabolites with important
pharmacological properties. Until recently, plant biologists were limited in their ability to …

Biosynthesis of tetrahydropapaverine and semisynthesis of papaverine in yeast

OK Jamil, A Cravens, JT Payne… - Proceedings of the …, 2022 - National Acad Sciences
Tetrahydropapaverine (THP) and papaverine are plant natural products with clinically
significant roles. THP is a precursor in the production of the drugs atracurium and …

Dual action anti‐inflammatory/antiviral isoquinoline alkaloids as potent naturally occurring anti‐SARS‐CoV‐2 agents: A combined pharmacological and medicinal …

M Valipour, A Hosseini, A Di Sotto… - Phytotherapy …, 2023 - Wiley Online Library
In the search for compounds that inhibit the SARS‐CoV‐2 after the onset of the COVID‐19
pandemic, isoquinoline‐containing alkaloids have been identified as compounds with high …

Papaver somniferum L. taxonomy, uses and new insight in poppy alkaloid pathways

F Labanca, J Ovesna, L Milella - Phytochemistry reviews, 2018 - Springer
Since ancient times, opium poppy (Papaver somniferum L.) is known for its medicinal
properties, related to its secondary metabolite content. Its most important secondary …

Transcriptome analysis of ripe and unripe fruit tissue of banana identifies major metabolic networks involved in fruit ripening process

MH Asif, D Lakhwani, S Pathak, P Gupta, SK Bag… - BMC plant biology, 2014 - Springer
Background Banana is one of the most important crop plants grown in the tropics and sub-
tropics. It is a climacteric fruit and undergoes ethylene dependent ripening. Once ripening is …

Insights into opium poppy (Papaver spp.) genetic diversity from genotyping-by-sequencing analysis

UVT Hong, M Tamiru-Oli, B Hurgobin, CR Okey… - Scientific Reports, 2022 - nature.com
Opium poppy (Papaver somniferum) is one of the world's oldest medicinal plants and a
versatile model system to study secondary metabolism. However, our knowledge of its …

Phloem-specific localization of benzylisoquinoline alkaloid metabolism in opium poppy

N Ozber, PJ Facchini - Journal of Plant Physiology, 2022 - Elsevier
Opium poppy is the only commercial source of the narcotic analgesics morphine and
codeine, and semi-synthetic derivatives of the natural opiate precursor thebaine, including …

Exploitation of next generation sequencing technologies for unraveling metabolic pathways in medicinal plants: A concise review

M Younessi-Hamzekhanlu, M Ozturk… - Industrial Crops and …, 2022 - Elsevier
Medicinal plants having high-value and unique active ingredients are attractive in different
industries, including pharmaceutical, food and cosmetic sectors. The phytochemicals in …