In this paper, we study the problem of multi-institutional regionalization of primary health
care units. The problem consists of deciding where to place new facilities, capacity …

Managerial and Business Economics (ME/BE) aims at using quantitative and computational
methods to make an efficient (ideally optimal) assignment of the scarce resources owned by …

The iterated greedy algorithm generates a sequence of solutions by iterating over a
constructive heuristic using destruction and construction phases. In the last few years, it has …

The lack of access to Second-level Health Care Services (SHCS) in developing countries is
primarily due to the scarcity of facilities and the limited investment of resources in the public …

In this paper, the problem of locating and upgrading primary health care units within a multi-
institutional public system is addressed. The problem is motivated by a real-world …

The ultimate purpose of portfolio investment is to reduce investment risk and improve total
return on the premise of ensuring reasonable allocation of capital. In this paper, we build a …

With almost 50% of annual commercial drug approvals being Personalised Medicine (PM)
and its huge potential to improve quality of life, this emerging medical sector has received …

The biopharmaceuticals developed under Personalised Medicine (PM) are the most
promising medical treatments of this century, yet their commercialisation on large scale …