The basics and underlying mechanisms of mucoadhesion

JD Smart - Advanced drug delivery reviews, 2005 - Elsevier
Mucoadhesion is where two surfaces, one of which is a mucous membrane, adhere to each
other. This has been of interest in the pharmaceutical sciences in order to enhance localised …

Pharmaceutical applications of mucoadhesion for the non‐oral routes

K Edsman, H Hägerström - Journal of pharmacy and …, 2005 - Wiley Online Library
The adhesion of pharmaceutical formulations to the mucosal tissue offers the possibility of
creating an intimate and prolonged contact at the site of administration. This prolonged …

Swelling behavior of acrylic acid hydrogels prepared by γ-radiation crosslinking of polyacrylic acid in aqueous solution

E Jabbari, S Nozari - European Polymer Journal, 2000 - Elsevier
Swelling behavior of anionic acrylic acid polyelectrolyte hydrogel synthesized by γ-radiation
crosslinking of polyacrylic acid in aqueous solution was investigated. Cross-linked …

Novel mucoadhesive buccal formulation containing metronidazole for the treatment of periodontal disease

L Perioli, V Ambrogi, D Rubini, S Giovagnoli… - Journal of controlled …, 2004 - Elsevier
Mucoadhesive tablets using different mixture of cellulose and polyacrylic derivatives were
prepared in order to obtain new formulations containing metronidazole for periodontal …

Ultrapure poly (vinyl alcohol) hydrogels with mucoadhesive drug delivery characteristics

NA Peppas, NK Mongia - European journal of pharmaceutics and …, 1997 - Elsevier
Poly (vinyl alcohol)(PVA) hydrogels were prepared by treating 15 or 20% aqueous PVA
solutions to repeated cycles of freezing for 6 or 12 h at− 20° C and thawing for 2 h at 25° C …

A rheological examination of the mucoadhesive/mucus interaction: the effect of mucoadhesive type and concentration

F Madsen, K Eberth, JD Smart - Journal of controlled release, 1998 - Elsevier
The ability of mucoadhesive polymers to produce a large increase in the resistance to
deformation when incorporated into a mucus gel, relative to when the mucus gel and test …

Mucoadhesive delivery systems. I. Evaluation of mucoadhesive polymers for buccal tablet formulation

NA Nafee, FA Ismail, NA Boraie… - Drug development and …, 2004 - Taylor & Francis
Different types of mucoadhesive polymers, intended for buccal tablet formulation, were
investigated for their comparative mucoadhesive force, swelling behavior, residence time …

A critical review about methodologies for the analysis of mucoadhesive properties of drug delivery systems

J Bassi da Silva, SBS Ferreira, O de Freitas… - Drug development …, 2017 - Taylor & Francis
Mucoadhesion is a useful strategy for drug delivery systems, such as tablets, patches, gels,
liposomes, micro/nanoparticles, nanosuspensions, microemulsions and colloidal …

Biophysical analysis of the molecular interactions between polysaccharides and mucin

B Menchicchi, JP Fuenzalida, A Hensel… - …, 2015 - ACS Publications
Mucoadhesive materials adhere persistently to mucosal surfaces. A mucoadhesive delivery
system could therefore facilitate the controlled release of drugs and optimize their …

Formulation of intranasal mucoadhesive temperature-mediated in situ gel containing ropinirole and evaluation of brain targeting efficiency in rats

S Khan, K Patil, N Bobade, P Yeole… - Journal of drug …, 2010 - Taylor & Francis
Mucoadhesive temperature-mediated in situ gel formulations using chitosan and hydroxyl
propyl methyl cellulose were used to enhance intranasal (in) delivery of the dopamine D2 …