Vision on Synthetic and Medicinal Facets of 1,2,4-Triazolo[3,4-b][1,3,4]thiadiazine Scaffold

R Aggarwal, M Hooda, P Kumar, G Sumran - Topics in Current Chemistry, 2022 - Springer
The present review article strives to compile the latest synthetic approaches for the synthesis
of triazolothiadiazine and its derivatives, along with their diverse pharmacological activities …

Stereoselective synthesis of dihydrothiadiazinoazines and dihydrothiadiazinoazoles and their pyrolytic desulfurization ring contraction

A Al-Etaibi, E John, MR Ibrahim, NA Al-Awadi… - Tetrahedron, 2011 - Elsevier
Intramolecular base catalyzed C–C bond formation led to exclusive stereoselective
syntheses of trans-6, 7-dihydro-5H-[1, 2, 4] triazolo [3, 4-b][1, 3, 4] thiadiazines, trans-7, 8 …

Synthesis of spiro derivatives of 1,2,3-triazolo[5,1-b][1,3,4]thiadiazines and biological activity thereof

TA Kalinina, OA Bystrykh, VA Pozdina… - Chemistry of …, 2015 - Springer
3-Cyclopentylidene (cyclohexylidene) amino-3 H-1, 2, 3-triazole-4-thiolates, formed via
Dimroth rearrangement of 1, 2, 3-thiadiazolylhydrazones of cyclopentanone and …

Intramolecular Cyclization of the ortho‐Substituted N‐arylquinone Imines under Basic and Thermal Conditions

ES Khodykina, DV Steglenko, EV Vetrova… - …, 2023 - Wiley Online Library
Abstract The S (O, N)‐benzyl ethers of N‐arylquinone imines undergo cyclization under the
action of bases to form products of the benzothiazol, benzoxazole, and benzimidazole …

6,7‐Dihydro‐5H‐1,2,4‐triazolo[3,4‐b][1,3,4]thiadiazine Ring Cleavage and Tautomerism of the Products: Experimental and Theoretical Study

AA Kolodina, AA Tsaturyan, MS Galkina… - …, 2020 - Wiley Online Library
Electronic effects of aryl substituents at the C (7)‐atom play a crucial role in the cleavage of a
six‐membered ring of 6, 7‐dihydro‐5H‐[1, 2, 4] triazolo [3, 4‐b][1, 3, 4] thiadiazines. Our …

The different modes of chiral [1, 2, 3] triazolo [5, 1-b][1, 3, 4] thiadiazines: Crystal packing, conformation investigation and cellular activity

KL Obydennov, TA Kalinina, OA Vysokova… - … Section C: Structural …, 2020 - journals.iucr.org
The crystal structures of four new chiral [1, 2, 3] triazolo [5, 1-b][1, 3, 4] thiadiazines are
described, namely, ethyl 5′-benzoyl-5′ H, 7′ H-spiro [cyclohexane-1, 6′-[1, 2, 3] …

[PDF][PDF] Review on Synthetic Strategies for 1, 3, 4-Thiadiazines and its Biological Activity

P Meshram, M Pardhi, P Bamgude, D Kamble… - 2024 - biointerfaceresearch.com
Heterocycles containing nitrogen and sulfur, known as thiazine, play a vital role in
pharmaceutical chemistry and agriculture chemistry. The thiadiazines compound contains …

Unusual cyclization of N-imidazolyl quinone imines with the formation of thiadiazole ring and its subsequent recyclization

AA Kolodina, DV Steglenko, ES Khodykina… - Mendeleev …, 2022 - Elsevier
Di-tert-butyl-4-{[2-(2-aryl-2-oxoethylthio)-1H-imidazol-1-yl] imino} cyclohexa-2, 5-dien-1-
ones under the action of bases give products of the 2, 3-dihydroimidazo [2, 1-b] thiazol-3-ol …

CИНТЕЗ И БИОЛОГИЧЕСКАЯ АКТИВНОСТЬ СПИРОПРОИЗВОДНЫХ 1,2,3-ТРИАЗОЛО[5,1-b][1,3,4]ТИАДИАЗИНОВ

ТА Калинина, ОA Быстрых, ВА Поздина… - Chemistry of …, 2015 - osi131.osi.lv
Перегруппировкой Димрота 1, 2, 3-тиадиазолилгидразонов циклопентанона и
циклогексанона в присутствии триэтиламина были получены 3-циклопентилиден …

Intramolecular cyclization of S-alkyl derivatives of aminomercaptoimidazoles and -benzimidazoles as a method for the annulation of the thiadiazine ring

NI Gaponenko, AA Kolodina, AV Lesin… - Russian Chemical …, 2012 - Springer
A method was developed for the annulation of the tetrahydrothiadiazine moiety to the
imidazole and benzimidazole rings through intramolecular cyclization of S-alkyl derivatives …