The discovery of Clustered Regularly Interspaced Palindromic Repeats (CRISPR) and its
associated Cas endonucleases in bacterial and archaeal species allowed scientists to …

Over the past 50 years, the number of overweight/obese people increased significantly,
making obesity a global public health challenge. Apart from rare monogenic forms, obesity is …

The advent of targeted therapies has led to tremendous improvements in treatment options
and their outcomes in the field of oncology. Yet, many cancers outsmart precision drugs by …

The study of diseases of the central nervous system (CNS) at the molecular level is
challenging because of the complexity of neural circuits and the huge number of specialized …

The global prevalence of obesity has reached epidemic levels, significantly elevating the
susceptibility to various cardiometabolic conditions and certain types of cancer. In addition to …

Remarkable progress has been made in the field of genome engineering after the discovery
of CRISPR/Cas9 in 2012 by Jennifer Doudna and Emmanuelle Charpentier. Compared to …

Alterations in transcriptional programs are a fundamental feature of prostate (PCa) and
breast cancer (BrCa), and frequently target the actions of the principal steroidal nuclear …

The term “genome” refers to all the genetic material for an organism including humans. On
the other hand, the term “epigenetics”, is a literal translation of “on top of the genetics” …