Choline supplements: An update

U Kansakar, V Trimarco, P Mone, F Varzideh… - Frontiers in …, 2023 - frontiersin.org
In this comprehensive review, we examine the main preclinical and clinical investigations
assessing the effects of different forms of choline supplementation currently available …

Prenatal and postnatal choline supplementation in fetal alcohol spectrum disorder

AM Ernst, BA Gimbel, E de Water, JK Eckerle… - Nutrients, 2022 - mdpi.com
Fetal alcohol spectrum disorder (FASD) is common and represents a significant public
health burden, yet very few interventions have been tested in FASD. Cognitive deficits are …

Long-term follow-up of a randomized controlled trial of choline for neurodevelopment in fetal alcohol spectrum disorder: corpus callosum white matter microstructure …

BA Gimbel, ME Anthony, AM Ernst, DJ Roediger… - Journal of …, 2022 - Springer
Background Fetal alcohol spectrum disorder (FASD) is a lifelong condition. Early
interventions targeting core neurocognitive deficits have the potential to confer long-term …

The role of maternal choline, folate and one‐carbon metabolism in mediating the impact of prenatal alcohol exposure on placental and fetal development

SE Steane, JSM Cuffe, KM Moritz - The Journal of Physiology, 2023 - Wiley Online Library
Prenatal alcohol consumption (PAE) may be associated with a broad spectrum of impacts,
ranging from no overt effects, to miscarriage, fetal growth restriction and fetal alcohol …

Evolution of the physical phenotype of fetal alcohol spectrum disorders from childhood through adolescence

SW Jacobson, HE Hoyme, RC Carter… - Alcoholism: Clinical …, 2021 - Wiley Online Library
Background This paper reports findings from the first longitudinal study on the evolution of
the physical phenotypes of fetal alcohol syndrome (FAS) and partial FAS (PFAS) from early …

Postnatal choline supplementation rescues deficits in synaptic plasticity following prenatal ethanol exposure

EL Grafe, MMM Wade, CE Hodson, JD Thomas… - Nutrients, 2022 - mdpi.com
Prenatal ethanol exposure (PNEE) is a leading cause of neurodevelopmental impairments,
yet treatments for individuals with PNEE are limited. Importantly, postnatal supplementation …

Current considerations for fetal alcohol spectrum disorders: identification to intervention

L Glass, EM Moore, SN Mattson - Current opinion in psychiatry, 2023 - journals.lww.com
Current considerations for fetal alcohol spectrum disorders:... : Current Opinion in Psychiatry
Current considerations for fetal alcohol spectrum disorders: identification to intervention …

Choline supplementation modifies the effects of developmental alcohol exposure on immune responses in adult rats

JA Baker, KR Breit, TS Bodnar, J Weinberg, JD Thomas - Nutrients, 2022 - mdpi.com
Prenatal alcohol exposure can disrupt the development of numerous systems, including the
immune system. Indeed, alterations in cytokine levels may contribute to the …

Inadequate choline intake in pregnant women in Germany

M Roeren, A Kordowski, C Sina, M Smollich - Nutrients, 2022 - mdpi.com
Choline is an essential nutrient that is involved in various developmental processes during
pregnancy. While the general adequate choline intake (AI) for adults has been set at 400 …

Mitigating the detrimental developmental impact of early fetal alcohol exposure using a maternal methyl donor‐enriched diet

M Breton‐Larrivée, E Elder, LM Legault… - The FASEB …, 2023 - Wiley Online Library
Fetal alcohol exposure at any stage of pregnancy can lead to fetal alcohol spectrum disorder
(FASD), a group of life‐long conditions characterized by congenital malformations, as well …