Epigenome-wide association study in Chinese monozygotic twins identifies DNA methylation loci associated with blood pressure

W Wang, J Yao, W Li, Y Wu, H Duan, C Xu, X Tian… - Clinical …, 2023 - Springer
Background Hypertension is a crucial risk factor for developing cardiovascular disease and
reducing life expectancy. We aimed to detect DNA methylation (DNAm) variants potentially …

Identification of key DNA methylation changes on fasting plasma glucose: a genome-wide DNA methylation analysis in Chinese monozygotic twins

W Wang, W Yao, Q Tan, S Li, H Duan, X Tian… - Diabetology & Metabolic …, 2023 - Springer
Background Elevated fasting plasma glucose (FPG) levels can increase morbidity and
mortality even when it is below the diagnostic threshold of type 2 diabetes mellitus (T2DM) …

DNA methylation and waist-to-hip ratio: an epigenome-wide association study in Chinese monozygotic twins

Y Wu, H Tian, W Wang, W Li, H Duan… - Journal of Endocrinological …, 2022 - Springer
Purpose Epigenetic signatures such as DNA methylation may be associated with specific
obesity traits. We performed an epigenome-wide association study (EWAS) by combining …

Co-methylation analyses identify CpGs associated with lipid traits in Chinese discordant monozygotic twins

Z Li, W Wang, W Li, H Duan, C Xu, X Tian… - Human Molecular …, 2024 - academic.oup.com
To control genetic background and early life milieu in genome-wide DNA methylation
analysis for blood lipids, we recruited Chinese discordant monozygotic twins to explore the …

Twin Studies: Current Status and Future Directions

K Ono - Journal of Atherosclerosis and Thrombosis, 2024 - jstage.jst.go.jp
Articles regarding risk factors for coronary artery disease using monozygotic (MZ) twins have
been recognized since the 1970s 1, 2). These methods of studying gene-environment …

Epigenome-wide association study identifies DNA methylation loci associated with handgrip strength in Chinese monozygotic twins

J Luo, W Wang, J Li, H Duan, C Xu, X Tian… - Frontiers in Cell and …, 2024 - frontiersin.org
Background: The decline in muscle strength and function with aging is well recognized, but
remains poorly characterized at the molecular level. Here, we report the epigenetic …