Oncoinformatic screening of the gene clusters involved in the HER2-positive breast cancer formation along with the in silico pharmacodynamic profiling of selective …

AKMH Morshed, S Al Azad, MAR Mia, MF Uddin… - Molecular Diversity, 2023 - Springer
The HER2-positive patients occupy~ 30% of the total breast cancer patients globally where
no prevalent drugs are available to mitigate the frequent metastasis clinically except …

[HTML][HTML] Point-specific interactions of isovitexin with the neighboring amino acid residues of the hACE2 receptor as a targeted therapeutic agent in suppressing the …

N Ferdausi, S Islam, FH Rimti, ST Quayum… - Journal of advanced …, 2022 - ncbi.nlm.nih.gov
Objective: Despite the development of several vaccines against severe acute respiratory
syndrome coronavirus-2, the need for an additional prophylactic agent is evident. In recent …

Target-specificity of different amyrin subunits in impeding HCV influx mechanism inside the human cells considering the quantum tunnel profiles and molecular strings …

A Jabin, MF Uddin, S Al Azad, A Rahman… - In Silico …, 2023 - Springer
HCV is a hepatotropic RNA virus recognized for its frequent virulence and fatality worldwide.
Despite many vaccine development programs underway, researchers are on a quest for …

[HTML][HTML] Revolutionizing of bioactive natural products in prostate cancer research and care: Promising discoveries and future directions

KTK Reddy, K Krishnan, P Shanmugasundaram… - Intelligent …, 2024 - Elsevier
Globally, prostate cancer (PCa) is one of the most common cancers to strike men. Diet and
lifestyle appear to have a significant impact on PCa biology and carcinogenesis. PCa is the …

WGS-based screening of the co-chaperone protein DjlA-induced curved DNA binding protein A (CbpA) from a new multidrug-resistant zoonotic mastitis-causing …

MH Rahman, S Al Azad, MF Uddin, M Farzana… - Molecular Diversity, 2023 - Springer
The research aimed to establish a multidrug-resistant Klebsiella pneumoniae-induced
genetic model for mastitis considering the alternative mechanisms of the DjlA-mediated …

[PDF][PDF] Quantitative analysis of the factors influencing IDA and TSH downregulation in correlation to the fluctuation of activated vitamin D3 in women

S Al Azad, S Ahmed, P Biswas, MAR Mia… - J Adv Biotechnol Exp …, 2022 - researchgate.net
Anemia and thyroid disorders are global health issues that affect all ages but are more
apparent in women. In this case, some serological components responsible for iron …

Pentafuhalol-B, a Phlorotannin from Brown Algae, Strongly Inhibits the PLK-1 Overexpression in Cancer Cells as Revealed by Computational Analysis

WA Ansari, SO Rab, M Saquib, A Sarfraz, MK Hussain… - Molecules, 2023 - mdpi.com
Polo-like kinase-1 (PLK-1) is an essential mitotic serine/threonine (Ser/Thr) kinase that
belongs to the Polo-like kinase (PLK) family and is overexpressed in non-small cell lung …

Computational identification of potential modulators of heme-regulated inhibitor (HRI) for pharmacological intervention against sickle cell disease

AJ Owoloye, SO Olubode, A Ogunleye… - Journal of …, 2024 - Taylor & Francis
Sickle cell disease (SCD) poses a significant health challenge and therapeutic approaches
often target fetal hemoglobin (HbF) to ameliorate symptoms. Hydroxyurea, a current …

Bioinformatics analysis and molecular dynamics simulations of azoreductases (AzrBmH2) from Bacillus megaterium H2 for the decolorization of commercial dyes

HA Oyewusi, RA Wahab, KA Akinyede… - Environmental Sciences …, 2024 - Springer
The present study aimed to investigate the decolorization of various commercial dyes by
azoreductases (AzrBmH21, AzrBmH22/3, and AzrBmH24/5) through bioinformatics means …

Employment-related musculoskeletal complications experienced by the physical therapists in Bangladesh: a comprehensive cross-sectional case study

A Hossain, TS Proma, R Raju, S Ahmed… - Bulletin of Faculty of …, 2022 - Springer
Background Dentists, nurses, and physical therapists have all been associated with an
increased risk of work-related diseases. The findings of studies in these different …