This review attempts to show that there may be a relationship between inflammatory
processes induced by chronic overstimulation of the renin-angiotensin system (RAS) and …

From an evolutionary point of view, vitamin D and melatonin appeared very early and share
functions related to defense mechanisms. In the current clinical setting, vitamin D is …

Although we lack enough evidence to justify supplementing with vitamin D in the prevention
and treatment of COVID-19 infection, it is increasingly feasible that this hypothesis is valid …

Obstructive nephropathy favors the progression to chronic kidney disease (CKD), a severe
health problem worldwide. The unilateral ureteral obstruction (UUO) model is used to study …

A growing body of literature suggests that higher serum 25-hydroxyvitamin D [25 (OH) D]
concentrations, either in utero or in early life, may reduce the risk of autism. For example, an …

Abstract Purpose of Review Here, we review the known relations between hypertension and
obesity to inflammation and postulate the endogenous protective effect of melatonin and its …

Kidney transplant recipients usually have low vitamin D levels, especially in the early
posttransplantation period, but the association between vitamin D status with renal …

Background: Kidney disease is a serious problem that adversely affects human health, but
critical knowledge is lacking on how to effectively treat established chronic kidney disease …

Insulin resistance (IR) is present in pathologies such as diabetes, obesity, metabolic
syndrome, impaired glucose tolerance, hypertension, inflammation, cardiac disease, and …

As a major social and economic burden for the healthcare system, kidney diseases
contribute to the constant increase of worldwide deaths. A deeper understanding of the …