Nitric oxide (NO) is an important signaling molecule that is involved in a wide range of
physiological and pathological events in biology. Metal coordination chemistry, especially …

Heme-copper oxidases (HCOs) are terminal enzymes on the mitochondrial or bacterial
respiratory electron transport chain, which utilize a unique heterobinuclear active site to …

Cytochrome c oxidase (C c O) is part of the respiratory chain and contributes to the
electrochemical membrane gradient in mitochondria as well as in many bacteria, as it uses …

Soluble methane monooxygenase (sMMO) is a multicomponent metalloenzyme that
catalyzes the conversion of methane to methanol at ambient temperature using a nonheme …

The fundamental chemistry underpinning aerobic life on Earth involves reduction of
dioxygen to water with concomitant proton translocation. This process is catalyzed by …

A role for conformational change in the coupling mechanism of cytochrome c oxidase is the
subject of controversy. Relatively small conformational changes have been reported in …

Cytochrome c oxidase (C c O), the terminal enzyme in the electron transfer chain,
translocates protons across the inner mitochondrial membrane by harnessing the free …

The periplasmic nitrate reductase (NapAB) from Cupriavidus necator is a heterodimeric
protein that belongs to the dimethyl sulfoxide reductase family of mononuclear Mo …

Ni-containing carbon monoxide dehydrogenases (CODH), present in many anaerobic
microorganisms, catalyze the reversible oxidation of CO to CO2 at the so-called C-cluster …

As a consumer of 95% of the oxygen we breathe, cytochrome c oxidase plays a major role in
the energy balance of the cell. Regulation of its oxygen reduction and proton pumping …