Chromosome engineering of Escherichia coli for constitutive production of salvianic acid A

L Zhou, Q Ding, GZ Jiang, ZN Liu, HY Wang… - Microbial Cell …, 2017 - Springer
Abstract Background Salvianic acid A (SAA), a valuable natural product from herbal plant
Salvia miltiorrhiza, exhibits excellent antioxidant activities on food industries and efficacious …

Suppression of Prolactin Secretion Partially Explains the Antidiabetic Effect of Bromocriptine in ob/ob Mice

IC Furigo, MF Suzuki, JE Oliveira… - …, 2019 - academic.oup.com
Previous studies have shown that bromocriptine mesylate (Bromo) lowers blood glucose
levels in adults with type 2 diabetes mellitus; however, the mechanism of action of the …

Long-Acting Human Growth Hormone Receptor Antagonists Produced in E. coli and Conjugated with Polyethylene Glycol

Y Wang, RJ Langley, K Tamshen… - Bioconjugate …, 2020 - ACS Publications
Growth hormone (GH) is a peptide hormone that mediates actions through binding to a cell
surface GH receptor (GHR). The GHR antagonist, B2036, combines an amino acid …

Efficient application of a baculovirus-silkworm larvae expression system for obtaining porcine circovirus type 2 virus-like particles for a vaccine

Q He, Z Cao, P Wang, Q Lu, H Zheng, J Sun - Archives of Virology, 2020 - Springer
Abstract Porcine circovirus type 2 (PCV2) is a major pathogen associated with swine
diseases. It is the smallest single-stranded DNA virus, and its genome contains four major …

High production and optimization of the method for obtaining pure recombinant human prolactin

R Affonso, CR Soares, MT Ribela, P Bartolini - Protein Expression and …, 2018 - Elsevier
Prolactin is a pituitary hormone that is involved diverse physiological functions, such as
lactation, reproduction, metabolism, osmoregulation, immunoregulation, and behavior. Its …

Determination of recombinant Interferon-α2 in E. coli periplasmic extracts by reversed-phase high-performance liquid chromatography

PVS Dias, FS Arthuso, JE Oliveira, MF Suzuki… - … of Chromatography B, 2018 - Elsevier
Reversed-phase high-performance liquid chromatography (RP-HPLC) has been used to
analyze Interferon α-2 (IFN-α2) as a pure protein or as a pharmaceutical preparation: a …

Periplasmic synthesis and purification of the human prolactin antagonist Δ1-11-G129R-hPRL

MF Suzuki, LA Almeida, SA Pomin, FD Silva, RP Freire… - AMB Express, 2021 - Springer
The human prolactin antagonist Δ1-11-G129R-hPRL is a 21.9 kDa recombinant protein with
188 amino acids that downregulates the proliferation of a variety of cells expressing …

[PDF][PDF] ADVANCE ARTICLE

IC Furigo, MF Suzuki, JE Oliveira, AM Ramos-Lobo… - repositorio.ipen.br
Previous studies have shown that bromocriptine mesylate (Bromo) lowers blood glucose
levels in adults with type 2 diabetes mellitus. However, the mechanism of action of the …

Growth hormone receptor agonists and antagonists: From protein expression and purification to long‐acting formulations

Y Wang, M Kim, C Buckley, HD Maynard… - Protein …, 2023 - Wiley Online Library
Recombinant human growth hormone (rhGH) and GH receptor antagonists (GHAs) are used
clinically to treat a range of disorders associated with GH deficiency or hypersecretion …

[PDF][PDF] Periplasmic synthesis and purification of the human prolactin antagonist Δ

MF Suzuki, LA Almeida, SA Pomin, FD Silva… - 2021 - amb-express.springeropen.com
The human prolactin antagonist Δ1-11-G129R-hPRL is a 21.9 kDa recombinant protein with
188 amino acids that downregulates the proliferation of a variety of cells expressing …