The corneal endothelium is responsible for maintaining the hydration of the cornea. This is
through a “Pump-Leak” mechanism where the active transport properties of the endothelium …

Corneal transparency is dependent on regulation of the hydration of the corneal stroma.
Water is driven into the cornea across the epithelial and endothelial cell layers by the …

purpose. Intercellular Ca 2+ wave propagation is a distinct form of cell–cell communication.
In corneal endothelial cells, intercellular Ca 2+ wave propagation evoked by a point …

Previous functional studies have demonstrated that muscle intracellular pH regulation is
mediated by sodium-coupled bicarbonate transport, Na+/H+ exchange, and Cl−/bicarbonate …

The four major sites for ocular water transport, the corneal epithelium and endothelium, the
ciliary epithelium, and the retinal pigment epithelium, are reviewed. The cornea has an …

The transient increase in [Ca2+] i in endothelial cells after stimulation with bradykinin can
account for the initiation but not the sustained production of nitric oxide (NO). Therefore, we …

Linear narrow wounds produced on cultured bovine corneal endothelial monolayers heal by
actin cable formation at the wound border and lamellar crawling of cells into the injured …

The cornea covers the anterior one-sixth of the total circumference of the globe (Fig. 1),
whereas the sclera covers the remaining five-sixths. The cornea is a clear, transparent …

Purpose.: Mutations in SLC4A11, a member of the SLC4 superfamily of bicarbonate
transporters, give rise to corneal endothelial cell dystrophies. SLC4A11 is a putative Na+ …

Human corneal endothelial cells (HCEnCs) form a monolayer of hexagonal cells whose
main function is to maintain corneal clarity by regulating corneal hydration. HCEnCs are …