S Svenson, DA Tomalia - Advanced drug delivery reviews, 2012 - Elsevier
The formation of particulate systems with well-defined sizes and shapes is of eminent interest in certain medical applications such as drug delivery, gene transfection, and …
MA Mintzer, MW Grinstaff - Chemical Society Reviews, 2011 - pubs.rsc.org
Since their development in the mid-80s, dendrimers have become prominent synthetic macromolecules in the field of biomedical science. This tutorial review begins by discussing …
U Boas, PMH Heegaard - Chemical Society Reviews, 2004 - pubs.rsc.org
Dendrimers are versatile, derivatisable, well-defined, compartmentalised chemical polymers with sizes and physicochemical properties resembling those of biomolecules eg proteins …
A Fahr, X Liu - Expert opinion on drug delivery, 2007 - Taylor & Francis
The drug candidates coming from combinatorial chemistry research and/or the drugs selected from biologically based high-throughput screening are quite often very lipophilic, as …
A Bunker, T Róg - Frontiers in Molecular Biosciences, 2020 - frontiersin.org
In this review, we outline the growing role that molecular dynamics simulation is able to play as a design tool in drug delivery. We cover both the pharmaceutical and computational …
We report various structural and conformational properties of generations 4, 5, and 6 PAMAM (polyamidoamine) dendrimer [EDA (ethylenediamine) core)] at various protonation …
D Wang, T Imae - Journal of the American Chemical Society, 2004 - ACS Publications
A strong fluorescence emission was observed from different kinds of dendrimers under acidic condition. There was a remarkable difference in fluorescence properties between …
GR Newkome, CD Shreiner - Polymer, 2008 - Elsevier
This review presents an overview of 1→ 2 branched dendrimers and dendrons, created by a divergent procedure, from their synthesis to modern day applications. The first members of …
M Ballauff, CN Likos - Angewandte Chemie International …, 2004 - Wiley Online Library
A variety of experimental and theoretical approaches show that, akin to linear polymers, dendrimers in good solvent conditions are best described as flexible macromolecular …