Simple Summary Cell migration is an essential process from embryogenesis to cell death.
This is tightly regulated by numerous proteins that help in proper functioning of the cell. In …

Intermediate filaments (IFs) are one of the three major elements of the cytoskeleton. Their
stability, intrinsic mechanical properties, and cell type–specific expression patterns …

Intermediate filaments (IFs) are key players in multiple cellular processes throughout human
tissues. Their biochemical and structural properties are important for understanding filament …

Nuclear structure and function are governed by lamins, which are intermediate filaments that
mostly consist of α-helices. Different lamin assembly models have been proposed based on …

Glial fibrillary acidic protein (GFAP) is an intermediate filament protein that is characteristic
for astrocytes and neural stem cells, and their malignant analogues in glioma. Since the …

Given the role of intermediate filaments (IFs) in normal cell physiology and scores of IF-
linked diseases, the importance of understanding their molecular structure is beyond doubt …

Lamin A is a nuclear intermediate filament protein critical for nuclear architecture and
mechanics and mutated in a wide range of human diseases. Yet little is known about the …

Understanding the structure and function of intermediate filaments (IFs) is necessary in order
to explain why more than 70 related IF genes have evolved in vertebrates while maintaining …

Astrocytes are fundamental in neural functioning and homeostasis in the central nervous
system. These cells respond to injuries and pathological conditions through astrogliosis, a …

The intermediate filament protein vimentin is involved in essential cellular processes,
including cell division and stress responses, as well as in the pathophysiology of cancer …