The influence of tramadol on bowel function: A randomised, placebo‐controlled trial

IM Larsen, T Okdahl, EB Mark… - Basic & Clinical …, 2024 - Wiley Online Library
Tramadol is a weak opioid used to treat moderate pain. Stronger opioids inhibit
gastrointestinal function, but little is known about the gastrointestinal effects of tramadol. Our …

Enhancing drug therapy in ostomy patients: Best practice recommendations for medication management

V Berger, M Reeh, M Scherer, S Härterich, S Möller… - PloS one, 2024 - journals.plos.org
Background Ostomy surgery is a common procedure that poses various challenges for
patients and healthcare professionals. There are numerous guidelines addressing different …

Effects of opium tincture on gastrointestinal function and motility in healthy volunteers: A magnetic resonance imaging study

EB Mark, T Okdahl, DG Kahlke… - …, 2024 - Wiley Online Library
Background Opioids inhibit motility and secretion of the gut and have been used for
antidiarrheal treatment for centuries. However, the underlying mechanisms of opium tincture …

Opium tincture has anti-propulsive effects in patients with chronic diarrhea: a randomized, placebo-controlled, and cross-over trial

T Okdahl, KL Høyer, CS Knoph… - Scandinavian Journal …, 2024 - Taylor & Francis
Objective Chronic diarrhea affects approximately 5% of the population. Opioids inhibit
gastrointestinal motility, and opium tincture has shown anti-propulsive effects in healthy, but …

Crohn's disease, irritable bowel syndrome, and chronic fatigue: the importance of communication and symptom management—a case report

J Haedrich, R Huber - Journal of Medical Case Reports, 2025 - Springer
Background Crohn's disease and irritable bowel syndrome may both cause abdominal pain
and diarrhea. Irritable bowel syndrome not only is an important differential diagnosis for …