CTX-M β-lactamases are prevalent antibiotic resistance enzymes and are notable for their
ability to rapidly hydrolyze the extended-spectrum cephalosporin, cefotaxime. We …

β-Lactams are the most widely prescribed class of antibiotics that inhibit penicillin-binding
proteins (PBPs), particularly transpeptidases that function in peptidoglycan synthesis. A …

In the antibacterial arsenal, β-lactams have held a prominent position, but increasing
resistance due to unauthorized use and genetic factors requires new strategies. Combining …

Inhibitors of α‐amylase have been developed to regulate postprandial blood glucose
fluctuation. The enzyme inhibition arises from direct or indirect inhibitor‐enzyme interactions …

Noncovalent interaction networks provide a powerful means to represent and analyze
protein structure. Such networks can represent both static structures and dynamic …

The relationship between protein dynamics and function is essential for understanding
biological processes and developing effective therapeutics. Functional sites within proteins …

Hotspots are interfacial residues in protein-protein complexes that contribute significantly to
complex stability. Methods for identifying interfacial residues in protein-protein complexes …

Enzymolysis Modes Trigger Diversity in Inhibitor‐α‐Amylase
Aggregating Behaviors and Activit Page 1 RESEARCH ARTICLE www.advancedscience.com …

Antimicrobial resistance is one of the biggest health problem, especially in the current period
of COVID-19 pandemic. Due to the unique membrane-destruction bactericidal mechanism …