PFAS: forever chemicals—persistent, bioaccumulative and mobile. Reviewing the status and the need for their phase out and remediation of contaminated sites
H Brunn, G Arnold, W Körner, G Rippen… - Environmental Sciences …, 2023 - Springer
Background Per-and polyfluorinated alkyl substances (PFAS) have received increasing
scientific and political attention in recent years. Several thousand commercially produced …
scientific and political attention in recent years. Several thousand commercially produced …
US drinking water quality: exposure risk profiles for seven legacy and emerging contaminants
R Levin, CM Villanueva, D Beene… - Journal of exposure …, 2024 - nature.com
Background Advances in drinking water infrastructure and treatment throughout the 20th
and early 21st century dramatically improved water reliability and quality in the United States …
and early 21st century dramatically improved water reliability and quality in the United States …
Sociodemographic factors are associated with the abundance of PFAS sources and detection in US community water systems
JM Liddie, LA Schaider… - Environmental Science & …, 2023 - ACS Publications
Drinking water contaminated by per-and polyfluoroalkyl substances (PFAS) is a widespread
public health concern, and exposure–response relationships are known to vary across …
public health concern, and exposure–response relationships are known to vary across …
[HTML][HTML] Exposure to perfluoroalkyl substances and risk of hepatocellular carcinoma in a multiethnic cohort
Background & Aims Exposure to poly-and perfluoroalkyl substances (PFAS), a class of
persistent organic pollutants, is ubiquitous. Animal studies suggest that PFAS may increase …
persistent organic pollutants, is ubiquitous. Animal studies suggest that PFAS may increase …
[HTML][HTML] PPARα/ACOX1 as a novel target for hepatic lipid metabolism disorders induced by per-and polyfluoroalkyl substances: an integrated approach
W Yang, X Ling, S He, H Cui, Z Yang, H An… - Environment …, 2023 - Elsevier
Background Per-and polyfluoroalkyl substances (PFAS) are persistent and ubiquitous
environmental contaminants with well-documented hepatotoxicity. However, the mechanistic …
environmental contaminants with well-documented hepatotoxicity. However, the mechanistic …
[HTML][HTML] Association of per-and polyfluoroalkyl substance exposure with fatty liver disease risk in US adults
Background & Aims Per-and polyfluoroalkyl substances (PFAS) are widespread pollutants
with demonstrated hepatotoxicity. Few studies have examined the association between …
with demonstrated hepatotoxicity. Few studies have examined the association between …
Assessing the hepatotoxicity of PFOA, PFOS, and 6: 2 Cl-PFESA in black-spotted frogs (Rana nigromaculata) and elucidating potential association with gut microbiota
H Lin, H Wu, F Liu, H Yang, L Shen, J Chen… - Environmental …, 2022 - Elsevier
Pollution caused by per-and polyfluoroalkyl substances (PFASs) has become a major global
concern. The association between PFAS-induced hepatotoxicity and gut microbiota in …
concern. The association between PFAS-induced hepatotoxicity and gut microbiota in …
Association of prenatal exposure to endocrine-disrupting chemicals with liver injury in children
Importance Prenatal exposures to endocrine-disrupting chemicals (EDCs) may increase the
risk for liver injury in children; however, human evidence is scarce, and previous studies …
risk for liver injury in children; however, human evidence is scarce, and previous studies …
Binding of per-and polyfluoroalkyl substances (pfas) to serum proteins: implications for toxicokinetics in humans
FC Fischer, S Ludtke, C Thackray… - Environmental …, 2024 - ACS Publications
Per-and polyfluoroalkyl substances (PFAS) are a diverse class of highly persistent
anthropogenic chemicals that are detectable in the serum of most humans. PFAS exposure …
anthropogenic chemicals that are detectable in the serum of most humans. PFAS exposure …
Paired liver: plasma PFAS concentration ratios from adolescents in the Teen-LABS study and derivation of empirical and mass balance models to predict and explain …
BO Baumert, FC Fischer, F Nielsen… - … science & technology, 2023 - ACS Publications
Animal studies have pointed at the liver as a hotspot for per-and polyfluoroalkyl substances
(PFAS) accumulation and toxicity; however, these findings have not been replicated in …
(PFAS) accumulation and toxicity; however, these findings have not been replicated in …