Endothelin (ET) peptides and their receptors are intimately involved in the physiological
control of systemic blood pressure and body Na homeostasis, exerting these effects through …

OVER the past few years, considerable evidence has accumulated to challenge the
accepted view of the regulation of adrenocortical function. Conventionally, the cortex and …

The regulatory mechanisms of the hypothalamo-pituitary-adrenal system were studied in
critically ill, intensive care unit patients. Serial measurements of immunoreactive ACTH-(1 …

We compared the effects of single doses of etomidate and thiopentone on adrenocortical
function in a randomised controlled clinical trial involving 35 critically ill patients who needed …

Sepsis and septic shock in response to bacterial or viral infections remain the major health
problem worldwide. Despite decades of intensive research and improvements in medical …

In addition to involvement in vascular endothelium-smooth muscle communication, the
secretion of and receptors for, endothelins are widely distibuted. Two cloned receptor …

The maintenance of life depends on the capacity of the organism to sustain its equilibrium
via allostasis'—the ability to achieve stability through change. Life-threatening disease …

The function of the corpus luteum (CL) is a key element in many reproductive processes
including ovulation, length of the estrous cycle, recognition of pregnancy and embryo …

Recent studies of adrenal function in conscious calves are reviewed. These have involved
collecting the whole of the adrenal effluent blood from the right adrenal gland at intervals …

Chronic kidney disease (CKD) causes salt-sensitive hypertension that is often resistant to
treatment and contributes to the progression of kidney injury and cardiovascular disease. A …