Pulmonary innate immune response determines the outcome of inflammation during pneumonia and sepsis-associated acute lung injury

V Kumar - Frontiers in immunology, 2020 - frontiersin.org
The lung is a primary organ for gas exchange in mammals that represents the largest
epithelial surface in direct contact with the external environment. It also serves as a crucial …

The Role of Macrophages in Staphylococcus aureus Infection

GR Pidwill, JF Gibson, J Cole, SA Renshaw… - Frontiers in …, 2021 - frontiersin.org
Staphylococcus aureus is a member of the human commensal microflora that exists,
apparently benignly, at multiple sites on the host. However, as an opportunist pathogen it …

Inhibition of Staphylococcus aureus α‐Hemolysin Production Using Nanocurcumin Capped Au@ZnO Nanocomposite

MS Jabir, TM Rashid, UM Nayef… - Bioinorganic …, 2022 - Wiley Online Library
Nanoparticles of gold with zinc oxide (Au@ ZnO NPs) were prepared by laser ablation and
then capped with curcumin nanoparticles (Cur‐Au@ ZnO NPs). The synthesized NPs were …

[HTML][HTML] Iron in infection and immunity

M Nairz, G Weiss - Molecular Aspects of Medicine, 2020 - Elsevier
Iron is an essential micronutrient for virtually all living cells. In infectious diseases, both
invading pathogens and mammalian cells including those of the immune system require iron …

Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management

SYC Tong, JS Davis, E Eichenberger… - Clinical microbiology …, 2015 - Am Soc Microbiol
Staphylococcus aureus is a major human pathogen that causes a wide range of clinical
infections. It is a leading cause of bacteremia and infective endocarditis as well as …

Exploring the Role of Staphylococcus aureus in Inflammatory Diseases

H Chen, J Zhang, Y He, Z Lv, Z Liang, J Chen, P Li… - Toxins, 2022 - mdpi.com
Staphylococcus aureus is a very common Gram-positive bacterium, and S. aureus infections
play an extremely important role in a variety of diseases. This paper describes the types of …

The era of thromboinflammation: platelets are dynamic sensors and effector cells during infectious diseases

L Guo, MT Rondina - Frontiers in immunology, 2019 - frontiersin.org
Platelets are anucleate cells produced by megakaryocytes. In recent years, a robust body of
literature supports the evolving role of platelets as key sentinel and effector cells in infectious …

Staphylococcus aureus α-Toxin: Nearly a Century of Intrigue

BJ Berube, J Bubeck Wardenburg - Toxins, 2013 - mdpi.com
Staphylococcus aureus secretes a number of host-injurious toxins, among the most
prominent of which is the small β-barrel pore-forming toxin α-hemolysin. Initially named …

The inflammasome in times of COVID-19

JC de Rivero Vaccari, WD Dietrich, RW Keane… - Frontiers in …, 2020 - frontiersin.org
Coronaviruses (CoVs) are members of the genus Betacoronavirus and the Coronaviridiae
family responsible for infections such as severe acute respiratory syndrome (SARS), Middle …

Role of pore-forming toxins in bacterial infectious diseases

FCO Los, TM Randis, RV Aroian… - … and Molecular Biology …, 2013 - Am Soc Microbiol
Pore-forming toxins (PFTs) are the most common bacterial cytotoxic proteins and are
required for virulence in a large number of important pathogens, including Streptococcus …