Rational combinations of immunotherapy with radiotherapy in ovarian cancer

FG Herrera, M Irving, LE Kandalaft, G Coukos - The Lancet Oncology, 2019 - thelancet.com
Except for its use in palliative care, radiotherapy has been largely abandoned in the
management of ovarian cancer because of the recognised efficacy and lower toxicity of …

Radiation sensitivity of human and murine peripheral blood lymphocytes, stem and progenitor cells

D Heylmann, F Rödel, T Kindler, B Kaina - Biochimica et Biophysica Acta …, 2014 - Elsevier
Immunodeficiency is a severe side effect of radiation therapy, notably at high radiation
doses. It may also impact healthy individuals exposed to environmental ionizing radiation …

Consensus guidelines for delineation of clinical target volume for intensity-modulated pelvic radiotherapy for the definitive treatment of cervix cancer

K Lim, W Small Jr, L Portelance, C Creutzberg… - International Journal of …, 2011 - Elsevier
PURPOSE: Accurate target definition is vitally important for definitive treatment of cervix
cancer with intensity-modulated radiotherapy (IMRT), yet a definition of clinical target volume …

Consensus guidelines for delineation of clinical target volume for intensity-modulated pelvic radiotherapy in postoperative treatment of endometrial and cervical …

W Small Jr, LK Mell, P Anderson, C Creutzberg… - International Journal of …, 2008 - Elsevier
PURPOSE: To develop an atlas of the clinical target volume (CTV) definitions for
postoperative radiotherapy of endometrial and cervical cancer to be used for planning pelvic …

Hematologic toxicity in RTOG 0418: a phase 2 study of postoperative IMRT for gynecologic cancer

AH Klopp, J Moughan, L Portelance, BE Miller… - International Journal of …, 2013 - Elsevier
PURPOSE: Intensity modulated radiation therapy (IMRT), compared with conventional 4-
field treatment, can reduce the volume of bone marrow irradiated. Pelvic bone marrow …

Bone marrow-sparing intensity modulated radiation therapy with concurrent cisplatin for stage IB-IVA cervical cancer: an international multicenter phase II clinical trial …

LK Mell, I Sirák, L Wei, R Tarnawski… - International Journal of …, 2017 - Elsevier
Purpose To test the hypothesis that intensity modulated radiation therapy (IMRT) reduces
acute hematologic and gastrointestinal (GI) toxicity for patients with locoregionally advanced …

Complications of pelvic radiation in patients treated for gynecologic malignancies

AN Viswanathan, LJ Lee, JR Eswara, NS Horowitz… - Cancer, 2014 - Wiley Online Library
Radiation therapy is a critical treatment modality in the management of patients with
gynecologic tumors. New highly conformal external‐beam and brachytherapy techniques …

Dose–volume effects for normal tissues in external radiotherapy: pelvis

C Fiorino, R Valdagni, T Rancati… - Radiotherapy and …, 2009 - Elsevier
A great deal of quantitative information regarding the dose–volume relationships of pelvic
organs at risk has been collected and analysed over the last 10 years. The need to improve …

Concurrent chemotherapy and intensity-modulated radiation therapy for anal canal cancer patients: a multicenter experience

JK Salama, LK Mell, DA Schomas, RC Miller… - Journal of clinical …, 2007 - ascopubs.org
Purpose To report a multicenter experience treating anal canal cancer patients with
concurrent chemotherapy and intensity-modulated radiation therapy (IMRT). Patients and …

Association between bone marrow dosimetric parameters and acute hematologic toxicity in anal cancer patients treated with concurrent chemotherapy and intensity …

LK Mell, DA Schomas, JK Salama, K Devisetty… - International Journal of …, 2008 - Elsevier
PURPOSE: To test the hypothesis that the volume of pelvic bone marrow (PBM) receiving 10
and 20 Gy or more (PBM-V10 and PBM-V20) is associated with acute hematologic toxicity …